MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
tryptophan 2'-monooxygenase : tms1 ( Agrobacterium tumefaciens )
tryptophan 2-monooxygenase Inferred from experiment : iaaM ( Pseudomonas savastanoi )

In Pathway: indole-3-acetate biosynthesis III (bacteria)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tryptophan 2-monooxygenase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -116.59701 Inferred by computational analysis [Latendresse13]

Citations: [Kosuge66]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00679 , Rhea:16165

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:P06617 , UniProt:RELATED-TO:P0A3V2 , UniProt:RELATED-TO:P0A3V3 , UniProt:RELATED-TO:Q04564 , UniProt:RELATED-TO:Q09109 , UniProt:RELATED-TO:Q44520 , UniProt:RELATED-TO:Q52367


Kosuge66: Kosuge T, Heskett MG, Wilson EE (1966). "Microbial synthesis and degradation of indole-3-acetic acid. I. The conversion of L-tryptophan to indole-3-acetamide by an enzyme system from Pseudomonas savastanoi." J Biol Chem 241(16);3738-44. PMID: 5916389

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Mar 31, 2015, BIOCYC13A.