Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 1.1.1.93

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.1.1.93

Enzymes and Genes:
D-malate / 3-isopropylmalate dehydrogenase (decarboxylating) Inferred from experiment : dmlA ( Escherichia coli K-12 substr. MG1655 )
tartrate dehydrogenase Inferred from experiment ( Pseudomonas putida )

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tartrate dehydrogenase

Enzyme Commission Synonyms: mesotartrate dehydrogenase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 3.541748 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
meso-tartrate and (R,R)-tartrate act as substrates. Requires Mn2+ and a monovalent cation.

Citations: [Kohn68]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R06180 , Rhea:15209

Relationship Links: BRENDA:EC:1.1.1.93 , ENZYME:EC:1.1.1.93 , IUBMB-ExplorEnz:EC:1.1.1.93 , UniProt:RELATED-TO:P42958 , UniProt:RELATED-TO:P76251 , UniProt:RELATED-TO:Q51945


References

Kohn68: Kohn LD, Packman PM, Allen RH, Jakoby WB (1968). "Tartaric acid metabolism. V. Crystalline tartrate dehydrogenase." J Biol Chem 243(10);2479-85. PMID: 4297261

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sat Dec 20, 2014, BIOCYC14B.