MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Escherichia coli K-12 substr. MG1655: D-malate / 3-isopropylmalate dehydrogenase (decarboxylating)Inferred from experiment: dmlA
Pseudomonas putida: tartrate dehydrogenaseInferred from experiment

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tartrate dehydrogenase

Enzyme Commission Synonyms: mesotartrate dehydrogenase

Taxonomic Range: Bacteria

Standard Gibbs Free Energy (ΔrG in kcal/mol): 3.541748Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
meso-tartrate and (R,R)-tartrate act as substrates. Requires Mn2+ and a monovalent cation.

Citations: [Kohn68 ]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R06180, Rhea:15209

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:P42958, UniProt:RELATED-TO:P76251, UniProt:RELATED-TO:Q51945


Kohn68: Kohn LD, Packman PM, Allen RH, Jakoby WB (1968). "Tartaric acid metabolism. V. Crystalline tartrate dehydrogenase." J Biol Chem 243(10);2479-85. PMID: 4297261

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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