|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
sphinganine + a long-chain acyl-CoA → a dihydroceramide + coenzyme A + H+ (2.3.1.-)
sphinganine + a long-chain acyl-CoA → a dihydroceramide + coenzyme A + H+ (no EC#)
phytosphingosine + a very long chain fatty acyl-CoA → a (4R)-4-hydroxysphinganine ceramide + coenzyme A + H+ (22.214.171.124)
Enzyme Commission Primary Name: sphingosine N-acyltransferase
Enzyme Commission Synonyms: ceramide synθse, sphingosine acyltransferase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 333.65692 [Latendresse13]
Enzyme Commission Summary:
Acts on sphingosine or its 2-epimer.
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