|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Enzymes and Genes:
S-formylglutathione hydrolase : frmB ( Escherichia coli K-12 substr. MG1655 )
S-formylglutathione hydrolase : yeiG ( Escherichia coli K-12 substr. MG1655 )
S-formylglutathione hydrolase ( Homo sapiens )
S-formylglutathione hydrolase : fghA ( Paracoccus denitrificans )
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: S-formylglutathione hydrolase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -5.1671143 [Latendresse13]
Enzyme Commission Summary:
Also hydrolyses S-acetylglutathione, but more slowly.
Harms96: Harms N, Ras J, Reijnders WN, van Spanning RJ, Stouthamer AH (1996). "S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification?." J Bacteriol 178(21);6296-9. PMID: 8892832
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