|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Protein-Modification Reactions|
|Reactions Classified By Substrate → Macromolecule Reactions → Protein-Reactions → Protein-Modification Reactions|
EC Number: 22.214.171.124
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655 :||ribonucleoside-triphosphate reductase
Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: ribonucleoside-triphosphate reductase
Enzyme Commission Synonyms: ribonucleotide reductase, 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -28.600891 [Latendresse13]
Enzyme Commission Summary:
Requires a cobamide coenzyme and ATP.
Blakley65: Blakley RL (1965). "Cobamides and ribonucleotide reduction. I. Cobamide stimulation of ribonucleotide reduction in extracts of Lactobacillus leichmannii." J Biol Chem 240;2173-80. PMID: 14299643
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