MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

Enzymes and Genes:

Rattus norvegicus: sterol 26-hydroxylaseInferred from experiment: Cyp27a1, Fdxr

Sub-reaction of:
1.14.15.h: 5β-cholestane-3α,7α-diol + 6 a reduced adrenodoxin + 5 H+ + 3 oxygen → (25R)-3α,7α-dihydroxy-5-β-cholestanate + 6 an oxidized adrenodoxin + 4 H2O

In Pathway: bile acid biosynthesis, neutral pathway

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Standard Gibbs Free Energy (ΔrG in kcal/mol): -90.00226Inferred by computational analysis [Latendresse13]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R04805

Revised 14-Sep-2012 by Caspi R, SRI International


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Fri Nov 27, 2015, BIOCYC13A.