MetaCyc Reaction: 1.3.8.-

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 1.3.8.-

Enzymes and Genes:

Methylomonas sp. 16a: diapophytoene desaturaseInferred from experiment: crtN
Staphylococcus aureus: dehydrosqualene desaturaseInferred from experiment: crtN

Sub-reaction of: 15-cis-4,4'-diapophytoene + 4 FAD + 4 H+ = all-trans-4,4'-diapolycopene + 4 FADH2,
1.3.8.o: 15-cis-4,4'-diapophytoene + 3 FAD + 3 H+ = all-trans-4,4'-diaponeurosporene + 3 FADH2

In Pathway: staphyloxanthin biosynthesis, 4,4'-diapolycopenedioate biosynthesis

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 1.3.8 -- With a flavin as acceptor

Standard Gibbs Free Energy (ΔrG in kcal/mol): -19.315643Inferred by computational analysis [Latendresse13]

This is one of several successive reactions catalyzed by 4,4'-diapophytoene desaturase.

Citations: [Raisig01, Wieland94 ]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: Rhea:31402

Revised 15-Jun-2011 by Caspi R, SRI International


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Raisig01: Raisig A, Sandmann G (2001). "Functional properties of diapophytoene and related desaturases of C(30) and C(40) carotenoid biosynthetic pathways." Biochim Biophys Acta 1533(2);164-70. PMID: 11566453

Wieland94: Wieland B, Feil C, Gloria-Maercker E, Thumm G, Lechner M, Bravo JM, Poralla K, Gotz F (1994). "Genetic and biochemical analyses of the biosynthesis of the yellow carotenoid 4,4'-diaponeurosporene of Staphylococcus aureus." J Bacteriol 176(24);7719-26. PMID: 8002598

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Sat Nov 28, 2015, BIOCYC13A.