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MetaCyc Reaction: 1.1.99.32

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.1.99.32

Enzymes and Genes:

Gluconobacter oxydans UV10 : L-sorbose dehydrogenase, FAD dependent Inferred from experiment : BAA13144
Ketogulonicigenium vulgare DSM 4025 : L-sorbose dehydrogenase Traceable author statement to experimental support Inferred from experiment

In Pathway: L-ascorbate biosynthesis III , 2-keto-L-gulonate biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: L-sorbose 1-dehydrogenase

Enzyme Commission Synonyms: SDH

Enzyme Commission Summary:
The product, L-sorbosone, is an intermediate in bacterial 2-keto-L-gulonic-acid formation. The activity of this membrane-bound enzyme is stimulated by Fe(III) or Co2+ but is inhibited by Cu2+. The enzyme is highly specific for L-sorbose as other sugars, such as glucose, mannitol and sorbitol, are not substrates. Phenazine methosulfate and DCIP can act as artificial acceptors.

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: Rhea:24878

Relationship Links: BRENDA:EC:1.1.99.32 , ENZYME:EC:1.1.99.32 , IUBMB-ExplorEnz:EC:1.1.99.32


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri Aug 28, 2015, biocyc12.