|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.1249
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: cobalt-precorrin-7 (C5)-methyltransferase
Enzyme Commission Synonyms: CbiE
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -44.6736 [Latendresse13]
Enzyme Commission Summary:
This enzyme catalyses the methylation at C-5 of cobalt-precorrin-7, a step in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway.
Santander06: Santander PJ, Kajiwara Y, Williams HJ, Scott AI (2006). "Structural characterization of novel cobalt corrinoids synthesized by enzymes of the vitamin B12 anaerobic pathway." Bioorg Med Chem 14(3);724-31. PMID: 16198574
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