Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.1.1.289

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.1.1.289

Enzymes and Genes:
cobalt-precorrin-7 (C5)-methyltransferase Inferred by computational analysis : cbiE ( Salmonella enterica enterica serovar Typhimurium )

In Pathway: cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: cobalt-precorrin-7 (C5)-methyltransferase

Enzyme Commission Synonyms: CbiE

Standard Gibbs Free Energy (ΔrG in kcal/mol): -44.6736 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
This enzyme catalyses the methylation at C-5 of cobalt-precorrin-7, a step in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway.

Citations: [Santander06]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R07775 , Rhea:34591

Relationship Links: BRENDA:EC:2.1.1.289 , ENZYME:EC:2.1.1.289 , IUBMB-ExplorEnz:EC:2.1.1.289

Credits:
Revised 03-Nov-2010 by Caspi R , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Santander06: Santander PJ, Kajiwara Y, Williams HJ, Scott AI (2006). "Structural characterization of novel cobalt corrinoids synthesized by enzymes of the vitamin B12 anaerobic pathway." Bioorg Med Chem 14(3);724-31. PMID: 16198574


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, BIOCYC14A.