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MetaCyc Reaction: 2.1.1.289

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.1.1.289

Enzymes and Genes:

Salmonella enterica enterica serovar Typhimurium : cobalt-precorrin-7 (C5)-methyltransferase Inferred by computational analysis : cbiE

In Pathway: cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: cobalt-precorrin-7 (C5)-methyltransferase

Enzyme Commission Synonyms: CbiE

Standard Gibbs Free Energy (ΔrG in kcal/mol): -52.055374 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
This enzyme catalyses the methylation at C-5 of cobalt-precorrin-7, a step in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway.

Citations: [Santander06]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R07775 , Rhea:34591

Relationship Links: BRENDA:EC:2.1.1.289 , ENZYME:EC:2.1.1.289 , IUBMB-ExplorEnz:EC:2.1.1.289

Credits:
Revised 03-Nov-2010 by Caspi R , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Santander06: Santander PJ, Kajiwara Y, Williams HJ, Scott AI (2006). "Structural characterization of novel cobalt corrinoids synthesized by enzymes of the vitamin B12 anaerobic pathway." Bioorg Med Chem 14(3);724-31. PMID: 16198574


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri Sep 4, 2015, biocyc14.