Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 1.5.1.21

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.5.1.21

Enzymes and Genes:
ketimine reductase mu-crystallin Inferred from experiment : CRYM ( Homo sapiens )
Δ1-piperideine-2-carboxylate reductase Inferred from experiment : dpkA ( Pseudomonas putida )

In Pathway: lysine degradation V , lysine degradation II (pipecolate pathway)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Instance reaction:
L-pipecolate + NAD+ = Δ1-piperideine-2-carboxylate + NADH + 2 H+ (1.5.1.21)

Enzyme Commission Primary Name: Δ1-piperideine-2-carboxylate reductase

Enzyme Commission Synonyms: 1,2-didehydropipecolate reductase, P2C reductase, 1,2-didehydropipecolic reductase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -24.103516 Inferred by computational analysis [Latendresse13]

Citations: [Payton82]

Gene-Reaction Schematic: ?

Instance reaction of [L-pipecolate + NAD(P)+ ← Δ1-piperideine-2-carboxylate + NAD(P)H + 2 H+] (1.5.1.21):
i1: L-pipecolate + NAD+ = Δ1-piperideine-2-carboxylate + NADH + 2 H+ (1.5.1.21)

Unification Links: KEGG:R02203 , Rhea:12524

Relationship Links: BRENDA:EC:1.5.1.21 , ENZYME:EC:1.5.1.21 , IUBMB-ExplorEnz:EC:1.5.1.21


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Payton82: Payton CW, Chang YF (1982). "delta1-piperideine-2-carboxylate reductase of Pseudomonas putida." J Bacteriol 149(3);864-71. PMID: 6801013


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Mon Dec 22, 2014, biocyc12.