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MetaCyc Reaction: 1.14.11.22

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.14.11.22

Enzymes and Genes:

Equisetum arvense : flavone synthase Inferred from experiment : FNS
Oryza sativa : flavone synthase I Inferred from experiment : FNS I-1
Petroselinum crispum : flavone synthase I Inferred from experiment : AY230247

In Pathway: isoflavonoid biosynthesis II , flavonoid biosynthesis (in equisetum) , luteolin biosynthesis

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: flavone synthase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -141.4001 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires ascorbate for full activity and Fe2+.

Citations: [Martens01, Lukacin01, Martens03]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R02445 , Rhea:32758

Relationship Links: BRENDA:EC:1.14.11.22 , ENZYME:EC:1.14.11.22 , IUBMB-ExplorEnz:EC:1.14.11.22


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Lukacin01: Lukacin R, Matern U, Junghanns KT, Heskamp ML, Britsch L, Forkmann G, Martens S (2001). "Purification and antigenicity of flavone synthase I from irradiated parsley cells." Arch Biochem Biophys 393(1);177-83. PMID: 11516175

Martens01: Martens S, Forkmann G, Matern U, Lukacin R (2001). "Cloning of parsley flavone synthase I." Phytochemistry 58(1);43-6. PMID: 11524111

Martens03: Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R (2003). "Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley." FEBS Lett 544(1-3);93-8. PMID: 12782296


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Wed Jul 1, 2015, biocyc13.