Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 1.14.11.22

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.14.11.22

Enzymes and Genes:
flavone synthase I Inferred from experiment : FNS I-1 ( Oryza sativa )
flavone synthase Inferred from experiment : FNS ( Equisetum arvense )
flavone synthase I Inferred from experiment : AY230247 ( Petroselinum crispum )

In Pathway: isoflavonoid biosynthesis II , flavonoid biosynthesis (in equisetum) , luteolin biosynthesis

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: flavone synthase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -141.4001 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires ascorbate for full activity and Fe2+.

Citations: [Martens01, Lukacin01, Martens03]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R02445 , Rhea:32758

Relationship Links: BRENDA:EC:1.14.11.22 , ENZYME:EC:1.14.11.22 , IUBMB-ExplorEnz:EC:1.14.11.22


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Lukacin01: Lukacin R, Matern U, Junghanns KT, Heskamp ML, Britsch L, Forkmann G, Martens S (2001). "Purification and antigenicity of flavone synthase I from irradiated parsley cells." Arch Biochem Biophys 393(1);177-83. PMID: 11516175

Martens01: Martens S, Forkmann G, Matern U, Lukacin R (2001). "Cloning of parsley flavone synthase I." Phytochemistry 58(1);43-6. PMID: 11524111

Martens03: Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R (2003). "Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley." FEBS Lett 544(1-3);93-8. PMID: 12782296


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, biocyc12.