MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Equisetum arvense: flavone synthaseInferred from experiment: FNS
Oryza sativa: flavone synthase IInferred from experiment: FNS I-1
Petroselinum crispum: flavone synthase IInferred from experiment: AY230247

In Pathway: isoflavonoid biosynthesis II, flavonoid biosynthesis (in equisetum), luteolin biosynthesis

Note that this reaction equation differs from the official Enzyme Commission reaction equation for this EC number, which can be found here .

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: flavone synthase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -141.4001Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires ascorbate for full activity and Fe2+.

Citations: [Martens01, Lukacin01, Martens03]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R02445, Rhea:32758

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Lukacin01: Lukacin R, Matern U, Junghanns KT, Heskamp ML, Britsch L, Forkmann G, Martens S (2001). "Purification and antigenicity of flavone synthase I from irradiated parsley cells." Arch Biochem Biophys 393(1);177-83. PMID: 11516175

Martens01: Martens S, Forkmann G, Matern U, Lukacin R (2001). "Cloning of parsley flavone synthase I." Phytochemistry 58(1);43-6. PMID: 11524111

Martens03: Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R (2003). "Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley." FEBS Lett 544(1-3);93-8. PMID: 12782296

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Mon Nov 30, 2015, BIOCYC11A.