Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 2.4.1.291

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.4.1.291

Enzymes and Genes:
N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-α-N-acetylgalactosaminyltransferase Inferred from experiment : pglJ ( Campylobacter jejuni )

In Pathway: undecaprenyl diphosphate-linked heptasaccharide biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: N-acetylgalactosamine-N,N′-diacetylbacillosaminyl-diphospho-undecaprenol 4-α-N-acetylgalactosaminyltransferase

Enzyme Commission Synonyms: PglJ

Standard Gibbs Free Energy (ΔrG in kcal/mol): 6.897583 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.

Citations: [Glover05, Chen07a]

Gene-Reaction Schematic: ?

Unification Links: Rhea:34543

Relationship Links: BRENDA:EC:2.4.1.291 , ENZYME:EC:2.4.1.291 , IUBMB-ExplorEnz:EC:2.4.1.291

Credits:
Created 02-Apr-2012 by Fulcher CA , SRI International
Revised 23-Aug-2012 by Caspi R , SRI International


References

Chen07a: Chen MM, Weerapana E, Ciepichal E, Stupak J, Reid CW, Swiezewska E, Imperiali B (2007). "Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway." Biochemistry 46(50);14342-8. PMID: 18034500

Glover05: Glover KJ, Weerapana E, Imperiali B (2005). "In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation." Proc Natl Acad Sci U S A 102(40);14255-9. PMID: 16186480

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc12.