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MetaCyc Reaction: 2.4.1.291

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 2.4.1.291

Enzymes and Genes:

Campylobacter jejuni: N-acetylgalactosamine-N,N'-diacetylbacillosaminyl-diphospho-undecaprenol 4-α-N-acetylgalactosaminyltransferaseInferred from experiment: pglJ

In Pathway: protein N-glycosylation (bacterial)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: N-acetylgalactosamine-N,N′-diacetylbacillosaminyl-diphospho-undecaprenol 4-α-N-acetylgalactosaminyltransferase

Enzyme Commission Synonyms: PglJ

Standard Gibbs Free Energy (ΔrG in kcal/mol): 6.897583Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Isolated from Campylobacter jejuni. Part of a bacterial N-linked glycosylation pathway.

Citations: [Glover05a, Chen07b]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: Rhea:34543

Relationship Links: BRENDA:EC:2.4.1.291, ENZYME:EC:2.4.1.291, IUBMB-ExplorEnz:EC:2.4.1.291

Credits:
Created 02-Apr-2012 by Fulcher CA, SRI International
Revised 23-Aug-2012 by Caspi R, SRI International


References

Chen07b: Chen MM, Weerapana E, Ciepichal E, Stupak J, Reid CW, Swiezewska E, Imperiali B (2007). "Polyisoprenol specificity in the Campylobacter jejuni N-linked glycosylation pathway." Biochemistry 46(50);14342-8. PMID: 18034500

Glover05a: Glover KJ, Weerapana E, Imperiali B (2005). "In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation." Proc Natl Acad Sci U S A 102(40);14255-9. PMID: 16186480

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue Feb 9, 2016, biocyc13.