|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: phospholipase A1
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -13.03833 [Latendresse13]
Enzyme Commission Summary:
This enzyme has a much broader specificity than EC 126.96.36.199 phospholipase A2. Requires Ca2+.
Instance reaction of [a 1-monoglyceride + H2O → a fatty acid + glycerol + H+] (188.8.131.52):
i7: 1-oleoylglycerol + H2O → glycerol + oleate + H+ (184.108.40.206)
Instance reactions of [a phosphatidylcholine + H2O → a 2-lyso-phosphatidylcholine + a fatty acid + H+] (220.127.116.11):
i4: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O → 1-18:2-lysophosphatidylcholine + palmitate + H+ (18.104.22.168)
i5: 1,2-dipalmitoyl-phosphatidylcholine + H2O → 1-16:0-2-lysophosphatidylcholine + palmitate + H+ (22.214.171.124)
Relationship Links: BRENDA:EC:126.96.36.199 , ENZYME:EC:188.8.131.52 , IUBMB-ExplorEnz:EC:184.108.40.206 , UniProt:RELATED-TO:P0A921 , UniProt:RELATED-TO:P18952 , UniProt:RELATED-TO:P51528 , UniProt:RELATED-TO:P53357 , UniProt:RELATED-TO:Q9PMU8
Kim11b: Kim EY, Seo YS, Kim WT (2011). "AtDSEL, an Arabidopsis cytosolic DAD1-like acylhydrolase, is involved in negative regulation of storage oil mobilization during seedling establishment." J Plant Physiol. PMID: 21477884
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493