|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: phospholipase A1
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -13.03833 [Latendresse13]
Enzyme Commission Summary:
This enzyme has a much broader specificity than EC 188.8.131.52 phospholipase A2. Requires Ca2+.
Instance reaction of [a 1-monoglyceride + H2O → a fatty acid + glycerol + H+] (184.108.40.206):
i8: 1-oleoyl-sn-glycerol + H2O → glycerol + oleate + H+ (220.127.116.11)
Instance reactions of [a phosphatidylcholine + H2O → a 1-acyl 2-lyso-phosphatidylcholine + a long-chain fatty acid + H+] (18.104.22.168):
i5: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O → 1-18:2-lysophosphatidylcholine + palmitate + H+ (22.214.171.124)
i6: 1,2-dipalmitoyl-phosphatidylcholine + H2O → 1-16:0-2-lysophosphatidylcholine + palmitate + H+ (126.96.36.199)
Relationship Links: BRENDA:EC:188.8.131.52 , ENZYME:EC:184.108.40.206 , IUBMB-ExplorEnz:EC:220.127.116.11 , UniProt:RELATED-TO:P0A921 , UniProt:RELATED-TO:P18952 , UniProt:RELATED-TO:P51528 , UniProt:RELATED-TO:P53357 , UniProt:RELATED-TO:Q9PMU8
Kim11a: Kim EY, Seo YS, Kim WT (2011). "AtDSEL, an Arabidopsis cytosolic DAD1-like acylhydrolase, is involved in negative regulation of storage oil mobilization during seedling establishment." J Plant Physiol. PMID: 21477884
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493