|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 22.214.171.124
Enzymes and Genes:
|Arabidopsis thaliana col:||phospholipase A1: DAD1|
phospholipase A1: AtLCAT3
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: phospholipase A1
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -13.03833 [Latendresse13]
Enzyme Commission Summary:
This enzyme has a much broader specificity than EC 126.96.36.199 phospholipase A2. Requires Ca2+.
Instance reaction of [a 1-monoglyceride + H2O → a fatty acid + glycerol + H+] (188.8.131.52):
i14: 1-oleoyl-sn-glycerol + H2O → glycerol + oleate + H+ (184.108.40.206)
Instance reactions of [a phosphatidylcholine + H2O → a 1-acyl 2-lyso-phosphatidylcholine + a long-chain fatty acid + H+] (220.127.116.11):
i11: 1,2-dipalmitoyl-phosphatidylcholine + H2O → 1-16:0-2-lysophosphatidylcholine + palmitate + H+ (18.104.22.168)
i12: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + H2O → 1-18:2-lysophosphatidylcholine + palmitate + H+ (22.214.171.124)
Relationship Links: BRENDA:EC:126.96.36.199, ENZYME:EC:188.8.131.52, IUBMB-ExplorEnz:EC:184.108.40.206, UniProt:RELATED-TO:P0A921, UniProt:RELATED-TO:P18952, UniProt:RELATED-TO:P51528, UniProt:RELATED-TO:P53357, UniProt:RELATED-TO:Q9PMU8
Kim11c: Kim EY, Seo YS, Kim WT (2011). "AtDSEL, an Arabidopsis cytosolic DAD1-like acylhydrolase, is involved in negative regulation of storage oil mobilization during seedling establishment." J Plant Physiol. PMID: 21477884
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