MetaCyc Reaction: 1.1.1.-

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.1.1.-

Enzymes and Genes:

Arabidopsis thaliana col : aldehyde reductase (chloroplastic) Inferred from experiment : ChlADR
aldehyde reductase (chloroplastic) Inferred from experiment : ChlADR
aldehyde reductase Inferred from experiment : SDR2
aldehyde reductase (cytosolic) Inferred from experiment : SDR1
aldo-keto reductase family 4 member C9 Inferred from experiment : AKR4C9
Escherichia coli K-12 substr. MG1655 : aldehyde reductase, NADPH-dependent : ahr
NADPH-dependent aldehyde reductase : yqhD
aldehyde reductase, NADPH-dependent : yahK
NADP+-dependent aldehyde reductase : ybbO

In Pathway: traumatin and (Z)-3-hexen-1-yl acetate biosynthesis , detoxification of reactive carbonyls in chloroplasts

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Direct generic reactions:
an alcohol + NADP+ = an aldehyde + NADPH + H+ (

an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ (

Enzyme Commission Primary Name: 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Standard Gibbs Free Energy (ΔrG in kcal/mol): -0.25650024 Inferred by computational analysis [Latendresse13]

Citations: [Yamauchi11]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Instance reaction of [an alcohol + NADP+ = an aldehyde + NADPH + H+] (
i1: (E)-2-hexenol + NADP+ ← (E)-2-hexenal + NADPH + H+ (1.1.1.-)


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Yamauchi11: Yamauchi Y, Hasegawa A, Taninaka A, Mizutani M, Sugimoto Y (2011). "NADPH-dependent Reductases Involved in the Detoxification of Reactive Carbonyls in Plants." J Biol Chem 286(9);6999-7009. PMID: 21169366

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sun Oct 4, 2015, BIOCYC14A.