MetaCyc Reaction: 1.1.1.-

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 1.1.1.-

Enzymes and Genes:

Arabidopsis thaliana col: aldehyde reductase (chloroplastic)Inferred from experiment: ChlADR
aldehyde reductase (chloroplastic)Inferred from experiment: ChlADR
aldehyde reductaseInferred from experiment: SDR2
aldehyde reductase (cytosolic)Inferred from experiment: SDR1
aldo-keto reductase family 4 member C9Inferred from experiment: AKR4C9
Escherichia coli K-12 substr. MG1655: aldehyde reductase, NADPH-dependent: yahK
aldehyde reductase, NADPH-dependent: ahr
NADP+-dependent aldehyde reductase: ybbO
NADPH-dependent aldehyde reductase: yqhD

In Pathway: traumatin and (Z)-3-hexen-1-yl acetate biosynthesis, detoxification of reactive carbonyls in chloroplasts

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Direct generic reactions:
an alcohol + NADP+ = an aldehyde + NADPH + H+ (

an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ (

Enzyme Commission Primary Name: 1.1.1 -- With NAD(+) or NADP(+) as acceptor

Standard Gibbs Free Energy (ΔrG in kcal/mol): -0.25650024Inferred by computational analysis [Latendresse13]

Citations: [Yamauchi11]

Gene-Reaction Schematic

Gene-Reaction Schematic

Instance reaction of [an alcohol + NADP+ = an aldehyde + NADPH + H+] (
i1: (E)-2-hexenol + NADP+ ← (E)-2-hexenal + NADPH + H+ (1.1.1.-)


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Yamauchi11: Yamauchi Y, Hasegawa A, Taninaka A, Mizutani M, Sugimoto Y (2011). "NADPH-dependent Reductases Involved in the Detoxification of Reactive Carbonyls in Plants." J Biol Chem 286(9);6999-7009. PMID: 21169366

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Sat Nov 28, 2015, BIOCYC13A.