|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.523
In Pathway: sulfoacetaldehyde degradation III
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: sulfoacetaldehyde reductase
Enzyme Commission Synonyms: isfD (gene name)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 1.2935181 [Latendresse13]
Enzyme Commission Summary:
Catalyses the reaction only in the opposite direction. The bacterium Chromohalobacter salexigens DSM 3043 possesses two enzymes that catalyse this reaction, a constitutive enzyme (encoded by isfD2) and an inducible enzyme (encoded by isfD). The latter is induced by taurine, and is responsible for most of the activity observed in taurine-grown cells.
Unification Links: Rhea:29594
Krejcik10: Krejcik Z, Hollemeyer K, Smits TH, Cook AM (2010). "Isethionate formation from taurine in Chromohalobacter salexigens: purification of sulfoacetaldehyde reductase." Microbiology 156(Pt 5);1547-55. PMID: 20133363
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493