MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
sulfoacetaldehyde reductase Inferred from experiment : isfD ( Chromohalobacter salexigens DSM 3043 )
sulfoacetaldehyde reductase Inferred from experiment : isfD ( Klebsiella oxytoca TauN1 )

In Pathway: sulfoacetaldehyde degradation III

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: sulfoacetaldehyde reductase

Enzyme Commission Synonyms: isfD (gene name)

Standard Gibbs Free Energy (ΔrG in kcal/mol): 1.2935181 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Catalyses the reaction only in the opposite direction. The bacterium Chromohalobacter salexigens DSM 3043 possesses two enzymes that catalyse this reaction, a constitutive enzyme (encoded by isfD2) and an inducible enzyme (encoded by isfD). The latter is induced by taurine, and is responsible for most of the activity observed in taurine-grown cells.

Citations: [Krejcik10]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: Rhea:29594

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:

Created 09-Feb-2011 by Caspi R , SRI International


Krejcik10: Krejcik Z, Hollemeyer K, Smits TH, Cook AM (2010). "Isethionate formation from taurine in Chromohalobacter salexigens: purification of sulfoacetaldehyde reductase." Microbiology 156(Pt 5);1547-55. PMID: 20133363

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Mar 31, 2015, BIOCYC13B.