Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

Enzymes and Genes:
flavonoid O-methyltransferase Inferred from experiment : OMT2 ( Triticum aestivum )

Sub-reaction of:
2.1.1.169: 3 S-adenosyl-L-methionine + tricetin → 3 S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin + 3 H+

In Pathway: O -methylation of tricetin

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.3599854 Inferred by computational analysis [Latendresse13]

Summary:
The enzyme from Triticum aestivum catalyses the sequential O-methylation of tricetin via 3'-O-methyltricetin, 3',5'-O-methyltricetin to 3',4',5'-O-trimethyltricetin [Zhou06a].

Citations: [Kornblatt08]

Gene-Reaction Schematic: ?

Unification Links: Rhea:27501

Credits:
Created 10-Aug-2010 by Kothari A , SRI International


References

Kornblatt08: Kornblatt JA, Zhou JM, Ibrahim RK (2008). "Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience." FEBS J 275(9);2255-66. PMID: 18397325

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Zhou06a: Zhou JM, Gold ND, Martin VJ, Wollenweber E, Ibrahim RK (2006). "Sequential O-methylation of tricetin by a single gene product in wheat." Biochim Biophys Acta 1760(7);1115-24. PMID: 16730127


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, biocyc12.