MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

Enzymes and Genes:

Triticum aestivum : flavonoid O-methyltransferase Inferred from experiment : OMT2

Sub-reaction of: 3 S-adenosyl-L-methionine + tricetin → 3 S-adenosyl-L-homocysteine + 3',4',5'-O-trimethyltricetin + 3 H+

In Pathway: O -methylation of tricetin

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Standard Gibbs Free Energy (ΔrG in kcal/mol): -4.3599854 Inferred by computational analysis [Latendresse13]

The enzyme from Triticum aestivum catalyses the sequential O-methylation of tricetin via 3'-O-methyltricetin, 3',5'-O-methyltricetin to 3',4',5'-O-trimethyltricetin [Zhou06].

Citations: [Kornblatt08]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: Rhea:27501

Created 10-Aug-2010 by Kothari A , SRI International


Kornblatt08: Kornblatt JA, Zhou JM, Ibrahim RK (2008). "Structure-activity relationships of wheat flavone O-methyltransferase: a homodimer of convenience." FEBS J 275(9);2255-66. PMID: 18397325

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Zhou06: Zhou JM, Gold ND, Martin VJ, Wollenweber E, Ibrahim RK (2006). "Sequential O-methylation of tricetin by a single gene product in wheat." Biochim Biophys Acta 1760(7);1115-24. PMID: 16730127

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, BIOCYC14B.