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MetaCyc Reaction: 2.7.1.4

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.4

Enzymes and Genes:
manno(fructo)kinase Inferred from experiment : mak ( Escherichia coli K-12 substr. MG1655 )
hexokinase Inferred from experiment ( Eimeria tenella )
fructokinase I Inferred from experiment ( Lactococcus lactis )
fructokinase Inferred from experiment : fruK ( Lactobacillus fermentum )
hexokinase Inferred from experiment : Hxk2 ( Nicotiana tabacum )
fructokinase Inferred from experiment : HXK1 ( Arabidopsis thaliana col )
fructokinase Inferred from experiment : frk ( Bifidobacterium longum )
fructokinase Inferred from experiment : scrK ( Klebsiella pneumoniae )
fructokinase Inferred from experiment : scrK ( Clostridium beijerinckii )
fructokinase (recombinant) Inferred from experiment ( Solanum lycopersicum )
fructokinase II Inferred from experiment ( Solanum lycopersicum )
fructokinase I Inferred from experiment ( Solanum lycopersicum )
fructokinase-Ib Inferred from experiment ( Hordeum vulgare )
fructokinase-Ia Inferred from experiment ( Hordeum vulgare )
fructokinase-II Inferred from experiment ( Hordeum vulgare )

In Pathway: sucrose degradation IV (sucrose phosphorylase) , heterolactic fermentation , mannitol cycle , D-sorbitol degradation I , sucrose degradation VII (sucrose 3-dehydrogenase) , sucrose degradation II (sucrose synthase) , sucrose degradation III (sucrose invertase) , galactose degradation IV , sucrose degradation I (sucrose phosphotransferase)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: fructokinase

Enzyme Commission Synonyms: fructokinase (phosphorylating), D-fructokinase, D-fructose(D-mannose)kinase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.545898 Inferred by computational analysis [Latendresse13]

Citations: [Bueding55, MEDINA56, Schmatz89]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00760 , Rhea:16125

Relationship Links: BRENDA:EC:2.7.1.4 , ENZYME:EC:2.7.1.4 , IUBMB-ExplorEnz:EC:2.7.1.4 , UniProt:RELATED-TO:O04897 , UniProt:RELATED-TO:O82616 , UniProt:RELATED-TO:P22824 , UniProt:RELATED-TO:P24261 , UniProt:RELATED-TO:P26420 , UniProt:RELATED-TO:P26984 , UniProt:RELATED-TO:P37829 , UniProt:RELATED-TO:P43468 , UniProt:RELATED-TO:P73521 , UniProt:RELATED-TO:Q9CFI9 , UniProt:RELATED-TO:Q9V0T7 , UniProt:RELATED-TO:Q03417 , UniProt:RELATED-TO:Q09124 , UniProt:RELATED-TO:Q42645

Credits:
Created 17-Jun-2010 by Fulcher CA , SRI International


References

Bueding55: Bueding E, Mackinnon JA (1955). "Hexokinases of Schistosoma mansoni." J Biol Chem 215(2);495-506. PMID: 13242546

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

MEDINA56: MEDINA A, SOLS A (1956). "A specific fructokinase in peas." Biochim Biophys Acta 19(2);378-9. PMID: 13315288

Schmatz89: Schmatz DM, Baginsky WF, Turner MJ (1989). "Evidence for and characterization of a mannitol cycle in Eimeria tenella." Mol Biochem Parasitol 32(2-3);263-70. PMID: 2538747


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Fri Mar 27, 2015, biocyc14.