MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Arabidopsis thaliana col: fructokinaseInferred from experiment: HXK1
Bifidobacterium longum: fructokinaseInferred from experiment: frk
Clostridium beijerinckii: fructokinaseInferred from experiment: scrK
Eimeria tenella: hexokinaseInferred from experiment
Escherichia coli K-12 substr. MG1655: manno(fructo)kinaseInferred from experiment: mak
Hordeum vulgare:
Klebsiella pneumoniae: fructokinaseInferred from experiment: scrK
Lactobacillus fermentum: fructokinaseInferred from experiment: fruK
Lactococcus lactis: fructokinase IInferred from experiment
Nicotiana tabacum: hexokinaseInferred from experiment: Hxk2
Solanum lycopersicum:

In Pathway: D-sorbitol degradation I, mannitol cycle, sucrose degradation IV (sucrose phosphorylase), sucrose degradation II (sucrose synthase), heterolactic fermentation, sucrose degradation III (sucrose invertase), sucrose degradation VII (sucrose 3-dehydrogenase), sucrose degradation I (sucrose phosphotransferase)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: fructokinase

Enzyme Commission Synonyms: fructokinase (phosphorylating), D-fructokinase, D-fructose(D-mannose)kinase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.545898Inferred by computational analysis [Latendresse13]

Citations: [Bueding55, Medina56, Schmatz89]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R00760, Rhea:16125

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:O04897, UniProt:RELATED-TO:O82616, UniProt:RELATED-TO:P22824, UniProt:RELATED-TO:P24261, UniProt:RELATED-TO:P26420, UniProt:RELATED-TO:P26984, UniProt:RELATED-TO:P37829, UniProt:RELATED-TO:P43468, UniProt:RELATED-TO:P73521, UniProt:RELATED-TO:Q9CFI9, UniProt:RELATED-TO:Q9V0T7, UniProt:RELATED-TO:Q03417, UniProt:RELATED-TO:Q09124, UniProt:RELATED-TO:Q42645

Created 17-Jun-2010 by Fulcher CA, SRI International


Bueding55: Bueding E, Mackinnon JA (1955). "Hexokinases of Schistosoma mansoni." J Biol Chem 215(2);495-506. PMID: 13242546

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Medina56: Medina A, Sols A (1956). "A specific fructokinase in peas." Biochim Biophys Acta 19(2);378-9. PMID: 13315288

Schmatz89: Schmatz DM, Baginsky WF, Turner MJ (1989). "Evidence for and characterization of a mannitol cycle in Eimeria tenella." Mol Biochem Parasitol 32(2-3);263-70. PMID: 2538747

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Wed Nov 25, 2015, biocyc12.