Join us at the Metabolomics Conference tutorial
June 28th 2015
Join us at the Metabolomics Conference tutorial
June 28th 2015
Join us at the Metabolomics Conference tutorial
June 28th 2015
Join us at the Metabolomics Conference tutorial
June 28th 2015
Join us at the Metabolomics Conference tutorial
June 28th 2015

MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Arabidopsis thaliana col : fructokinase Inferred from experiment : HXK1
Bifidobacterium longum : fructokinase Inferred from experiment : frk
Clostridium beijerinckii : fructokinase Inferred from experiment : scrK
Eimeria tenella : hexokinase Inferred from experiment
Escherichia coli K-12 substr. MG1655 : manno(fructo)kinase Inferred from experiment : mak
Hordeum vulgare :
Klebsiella pneumoniae : fructokinase Inferred from experiment : scrK
Lactobacillus fermentum : fructokinase Inferred from experiment : fruK
Lactococcus lactis : fructokinase I Inferred from experiment
Nicotiana tabacum : hexokinase Inferred from experiment : Hxk2
Solanum lycopersicum :

In Pathway: sucrose degradation IV (sucrose phosphorylase) , heterolactic fermentation , D-sorbitol degradation I , sucrose degradation VII (sucrose 3-dehydrogenase) , sucrose degradation II (sucrose synthase) , sucrose degradation III (sucrose invertase) , galactose degradation IV , sucrose degradation I (sucrose phosphotransferase) , mannitol cycle

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: fructokinase

Enzyme Commission Synonyms: fructokinase (phosphorylating), D-fructokinase, D-fructose(D-mannose)kinase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.545898 Inferred by computational analysis [Latendresse13]

Citations: [Bueding55, MEDINA56, Schmatz89]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00760 , Rhea:16125

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:O04897 , UniProt:RELATED-TO:O82616 , UniProt:RELATED-TO:P22824 , UniProt:RELATED-TO:P24261 , UniProt:RELATED-TO:P26420 , UniProt:RELATED-TO:P26984 , UniProt:RELATED-TO:P37829 , UniProt:RELATED-TO:P43468 , UniProt:RELATED-TO:P73521 , UniProt:RELATED-TO:Q9CFI9 , UniProt:RELATED-TO:Q9V0T7 , UniProt:RELATED-TO:Q03417 , UniProt:RELATED-TO:Q09124 , UniProt:RELATED-TO:Q42645

Created 17-Jun-2010 by Fulcher CA , SRI International


Bueding55: Bueding E, Mackinnon JA (1955). "Hexokinases of Schistosoma mansoni." J Biol Chem 215(2);495-506. PMID: 13242546

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

MEDINA56: MEDINA A, SOLS A (1956). "A specific fructokinase in peas." Biochim Biophys Acta 19(2);378-9. PMID: 13315288

Schmatz89: Schmatz DM, Baginsky WF, Turner MJ (1989). "Evidence for and characterization of a mannitol cycle in Eimeria tenella." Mol Biochem Parasitol 32(2-3);263-70. PMID: 2538747

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Jun 30, 2015, biocyc14.