MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Arabidopsis thaliana col : fructokinase Inferred from experiment : HXK1
Bifidobacterium longum : fructokinase Inferred from experiment : frk
Clostridium beijerinckii : fructokinase Inferred from experiment : scrK
Eimeria tenella : hexokinase Inferred from experiment
Escherichia coli K-12 substr. MG1655 : manno(fructo)kinase Inferred from experiment : mak
Hordeum vulgare :
Klebsiella pneumoniae : fructokinase Inferred from experiment : scrK
Lactobacillus fermentum : fructokinase Inferred from experiment : fruK
Lactococcus lactis : fructokinase I Inferred from experiment
Nicotiana tabacum : hexokinase Inferred from experiment : Hxk2
Solanum lycopersicum :

In Pathway: sucrose degradation IV (sucrose phosphorylase) , heterolactic fermentation , D-sorbitol degradation I , sucrose degradation VII (sucrose 3-dehydrogenase) , sucrose degradation II (sucrose synthase) , sucrose degradation III (sucrose invertase) , galactose degradation IV , sucrose degradation I (sucrose phosphotransferase) , mannitol cycle

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: fructokinase

Enzyme Commission Synonyms: fructokinase (phosphorylating), D-fructokinase, D-fructose(D-mannose)kinase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.545898 Inferred by computational analysis [Latendresse13]

Citations: [Bueding55, MEDINA56, Schmatz89]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00760 , Rhea:16125

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:O04897 , UniProt:RELATED-TO:O82616 , UniProt:RELATED-TO:P22824 , UniProt:RELATED-TO:P24261 , UniProt:RELATED-TO:P26420 , UniProt:RELATED-TO:P26984 , UniProt:RELATED-TO:P37829 , UniProt:RELATED-TO:P43468 , UniProt:RELATED-TO:P73521 , UniProt:RELATED-TO:Q9CFI9 , UniProt:RELATED-TO:Q9V0T7 , UniProt:RELATED-TO:Q03417 , UniProt:RELATED-TO:Q09124 , UniProt:RELATED-TO:Q42645

Created 17-Jun-2010 by Fulcher CA , SRI International


Bueding55: Bueding E, Mackinnon JA (1955). "Hexokinases of Schistosoma mansoni." J Biol Chem 215(2);495-506. PMID: 13242546

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

MEDINA56: MEDINA A, SOLS A (1956). "A specific fructokinase in peas." Biochim Biophys Acta 19(2);378-9. PMID: 13315288

Schmatz89: Schmatz DM, Baginsky WF, Turner MJ (1989). "Evidence for and characterization of a mannitol cycle in Eimeria tenella." Mol Biochem Parasitol 32(2-3);263-70. PMID: 2538747

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Sat Oct 10, 2015, biocyc14.