Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.7.1.4

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.7.1.4

Enzymes and Genes:
manno(fructo)kinase Inferred from experiment : mak ( Escherichia coli K-12 substr. MG1655 )
hexokinase Inferred from experiment ( Eimeria tenella )
fructokinase I Inferred from experiment ( Lactococcus lactis )
fructokinase Inferred from experiment : fruK ( Lactobacillus fermentum )
hexokinase Inferred from experiment : Hxk2 ( Nicotiana tabacum )
fructokinase Inferred from experiment : HXK1 ( Arabidopsis thaliana col )
fructokinase Inferred from experiment : frk ( Bifidobacterium longum )
fructokinase Inferred from experiment : scrK ( Klebsiella pneumoniae )
fructokinase Inferred from experiment : scrK ( Clostridium beijerinckii )
fructokinase (recombinant) Inferred from experiment ( Solanum lycopersicum )
fructokinase II Inferred from experiment ( Solanum lycopersicum )
fructokinase I Inferred from experiment ( Solanum lycopersicum )
fructokinase-Ib Inferred from experiment ( Hordeum vulgare )
fructokinase-Ia Inferred from experiment ( Hordeum vulgare )
fructokinase-II Inferred from experiment ( Hordeum vulgare )

In Pathway: sucrose degradation IV (sucrose phosphorylase) , heterolactic fermentation , sucrose degradation I (sucrose phosphotransferase) , mannitol cycle , D-sorbitol degradation I , sucrose degradation VII (sucrose 3-dehydrogenase) , sucrose degradation II (sucrose synthase) , sucrose degradation III (sucrose invertase) , galactose degradation IV

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: fructokinase

Enzyme Commission Synonyms: fructokinase (phosphorylating), D-fructokinase, D-fructose(D-mannose)kinase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.545898 Inferred by computational analysis [Latendresse13]

Citations: [Bueding55, MEDINA56, Schmatz89]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R00760 , Rhea:16125

Relationship Links: BRENDA:EC:2.7.1.4 , ENZYME:EC:2.7.1.4 , IUBMB-ExplorEnz:EC:2.7.1.4 , UniProt:RELATED-TO:O04897 , UniProt:RELATED-TO:O82616 , UniProt:RELATED-TO:P22824 , UniProt:RELATED-TO:P24261 , UniProt:RELATED-TO:P26420 , UniProt:RELATED-TO:P26984 , UniProt:RELATED-TO:P37829 , UniProt:RELATED-TO:P43468 , UniProt:RELATED-TO:P73521 , UniProt:RELATED-TO:Q9CFI9 , UniProt:RELATED-TO:Q9V0T7 , UniProt:RELATED-TO:Q03417 , UniProt:RELATED-TO:Q09124 , UniProt:RELATED-TO:Q42645

Credits:
Created 17-Jun-2010 by Fulcher CA , SRI International


References

Bueding55: Bueding E, Mackinnon JA (1955). "Hexokinases of Schistosoma mansoni." J Biol Chem 215(2);495-506. PMID: 13242546

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

MEDINA56: MEDINA A, SOLS A (1956). "A specific fructokinase in peas." Biochim Biophys Acta 19(2);378-9. PMID: 13315288

Schmatz89: Schmatz DM, Baginsky WF, Turner MJ (1989). "Evidence for and characterization of a mannitol cycle in Eimeria tenella." Mol Biochem Parasitol 32(2-3);263-70. PMID: 2538747


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc14.