Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: [no EC number assigned]

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

In Pathway: thyroid hormone metabolism II (via conjugation and/or degradation)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Marked as unbalanced.

Standard Gibbs Free Energy (ΔrG in kcal/mol): -40.226536 Inferred by computational analysis [Latendresse13]

Summary:
This reaction has been postulated to involve either transamination, or oxidative deamination, with the latter mechanism more likely (reviewed in [Wu05e]).


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Wu05e: Wu SY, Green WL, Huang WS, Hays MT, Chopra IJ (2005). "Alternate pathways of thyroid hormone metabolism." Thyroid 15(8);943-58. PMID: 16131336


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, biocyc14.