MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Mesorhizobium loti: pyridoxal 4-dehydrogenaseInferred from experiment: pldh-t
Saccharomyces cerevisiae: 3-oxoacyl-[acyl-carrier-protein] reductase: OAR1

In Pathway: vitamin B6 degradation

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: pyridoxal 4-dehydrogenase

Enzyme Commission Synonyms: pyridoxal dehydrogenase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -20.377228Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The enzyme acts on the hemiacetal form of the substrate.

Citations: [Burg69]

Gene-Reaction Schematic

Gene-Reaction Schematic

Instance reactions of [a (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ ← a 3-oxoacyl-[acp] + NADPH + H+] (
i1: a (3R)-3-hydroxybutanoyl-[acp] + NADP+ ← an acetoacetyl-[acp] + NADPH + H+ (

i2: a (3R)-3-hydroxybehenoyl-[acp] + NADP+ = a 3-oxo-behenoyl-[acp] + NADPH + H+ (

Unification Links: KEGG:R01707, Rhea:21339

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Burg69: Burg RW, Snell EE (1969). "The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4-pyridoxolactonase." J Biol Chem 244(10);2585-9. PMID: 4306030

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Mon Nov 30, 2015, BIOCYC13A.