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Metabolic Modeling Tutorial
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MetaCyc Reaction: 3.5.3.16

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.3.16

Enzymes and Genes:
methylguanidine amidinohydrolase Inferred from experiment ( Alcaligenes sp. N-42 )

In Pathway: creatinine degradation III

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: methylguanidinase

Enzyme Commission Synonyms: methylguanidine hydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 15.267002 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Acts on some other alkylguanidines, but very slowly.

Citations: [Nakajima80]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R01589 , Rhea:11764

Relationship Links: BRENDA:EC:3.5.3.16 , ENZYME:EC:3.5.3.16 , IUBMB-ExplorEnz:EC:3.5.3.16


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Nakajima80: Nakajima M, Shirokane Y, Mizusawa K (1980). "A new amidinohydrolase, methylguanidine amidinohydrolase from Alcaligenes sp. N-42." FEBS Lett 110(1);43-6. PMID: 7353662


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Jan 29, 2015, biocyc12.