MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Alcaligenes sp. N-42: methylguanidine amidinohydrolaseInferred from experiment

In Pathway: creatinine degradation III

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: methylguanidinase

Enzyme Commission Synonyms: methylguanidine hydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 15.267002Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Acts on some other alkylguanidines, but very slowly.

Citations: [Nakajima80]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R01589, Rhea:11764

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Nakajima80: Nakajima M, Shirokane Y, Mizusawa K (1980). "A new amidinohydrolase, methylguanidine amidinohydrolase from Alcaligenes sp. N-42." FEBS Lett 110(1);43-6. PMID: 7353662

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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