|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 188.8.131.52
Enzymes and Genes:
|Escherichia coli K-12 substr. MG1655 :||D-mannonate oxidoreductase
|Thermotoga maritima :||D-mannonate dehydrogenase
In Pathway: D-fructuronate degradation
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: fructuronate reductase
Enzyme Commission Synonyms: mannonate oxidoreductase, mannonic dehydrogenase, D-mannonate dehydrogenase, D-mannonate:NAD oxidoreductase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 1.0817871 [Latendresse13]
Enzyme Commission Summary:
Also reduces D-tagaturonate.
Relationship Links: BRENDA:EC:184.108.40.206 , ENZYME:EC:220.127.116.11 , IUBMB-ExplorEnz:EC:18.104.22.168 , UniProt:RELATED-TO:P33029 , UniProt:RELATED-TO:P39160 , UniProt:RELATED-TO:P77260 , UniProt:RELATED-TO:Q9CF49
Hickman60: Hickman J, Ashwell G (1960). "Uronic acid metabolism in bacteria. II. Purification and properties of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia coli." J Biol Chem 235;1566-70. PMID: 14401695
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