MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Aurantimonas manganoxydans SI85-9A1 : manganese-oxidizing peroxidase Inferred from experiment : mopA
Erythrobacter sp. SD-21 : manganese-oxidizing peroxidase Inferred from experiment : mopA
Phanerochaete chrysosporium : manganese peroxidase 1 Inferred from experiment : MNP1

In Pathway: manganese oxidation I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: manganese peroxidase

Enzyme Commission Synonyms: peroxidase-M2, Mn-dependent (NADH-oxidizing) peroxidase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -64.81047 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
A hemoprotein. Involved in the oxidative degradation of lignin in white rot basidiomycetes.

Citations: [Glenn86, Paszczynski86, Wariishi88]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00011 , Rhea:22776

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:P19136 , UniProt:RELATED-TO:P78733 , UniProt:RELATED-TO:Q7M4V9 , UniProt:RELATED-TO:Q7M4X2 , UniProt:RELATED-TO:Q9URB1 , UniProt:RELATED-TO:Q02567 , UniProt:RELATED-TO:Q12332 , UniProt:RELATED-TO:Q12597 , UniProt:RELATED-TO:Q99058


Glenn86: Glenn JK, Akileswaran L, Gold MH (1986). "Mn(II) oxidation is the principal function of the extracellular Mn-peroxidase from Phanerochaete chrysosporium." Arch Biochem Biophys 251(2);688-96. PMID: 3800395

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Paszczynski86: Paszczynski A, Huynh VB, Crawford R (1986). "Comparison of ligninase-I and peroxidase-M2 from the white-rot fungus Phanerochaete chrysosporium." Arch Biochem Biophys 244(2);750-65. PMID: 3080953

Wariishi88: Wariishi H, Akileswaran L, Gold MH (1988). "Manganese peroxidase from the basidiomycete Phanerochaete chrysosporium: spectral characterization of the oxidized states and the catalytic cycle." Biochemistry 27(14);5365-70. PMID: 3167051

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Wed Oct 7, 2015, BIOCYC14A.