Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 1.11.1.13

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 1.11.1.13

Enzymes and Genes:
manganese-oxidizing peroxidase Inferred from experiment : mopA ( Erythrobacter sp. SD-21 )
manganese-oxidizing peroxidase Inferred from experiment : mopA ( Aurantimonas manganoxydans SI85-9A1 )
manganese peroxidase 1 Inferred from experiment : MNP1 ( Phanerochaete chrysosporium )

In Pathway: manganese oxidation I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: manganese peroxidase

Enzyme Commission Synonyms: peroxidase-M2, Mn-dependent (NADH-oxidizing) peroxidase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -64.81047 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
A hemoprotein. Involved in the oxidative degradation of lignin in white rot basidiomycetes.

Citations: [Glenn86, Paszczynski86, Wariishi88]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R00011 , Rhea:22776

Relationship Links: BRENDA:EC:1.11.1.13 , ENZYME:EC:1.11.1.13 , IUBMB-ExplorEnz:EC:1.11.1.13 , UniProt:RELATED-TO:P19136 , UniProt:RELATED-TO:P78733 , UniProt:RELATED-TO:Q7M4V9 , UniProt:RELATED-TO:Q7M4X2 , UniProt:RELATED-TO:Q9URB1 , UniProt:RELATED-TO:Q02567 , UniProt:RELATED-TO:Q12332 , UniProt:RELATED-TO:Q12597 , UniProt:RELATED-TO:Q99058


References

Glenn86: Glenn JK, Akileswaran L, Gold MH (1986). "Mn(II) oxidation is the principal function of the extracellular Mn-peroxidase from Phanerochaete chrysosporium." Arch Biochem Biophys 251(2);688-96. PMID: 3800395

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Paszczynski86: Paszczynski A, Huynh VB, Crawford R (1986). "Comparison of ligninase-I and peroxidase-M2 from the white-rot fungus Phanerochaete chrysosporium." Arch Biochem Biophys 244(2);750-65. PMID: 3080953

Wariishi88: Wariishi H, Akileswaran L, Gold MH (1988). "Manganese peroxidase from the basidiomycete Phanerochaete chrysosporium: spectral characterization of the oxidized states and the catalytic cycle." Biochemistry 27(14);5365-70. PMID: 3167051


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Tue Nov 25, 2014, biocyc13.