MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: malonyl-CoA decarboxylase

Enzyme Commission Synonyms: malonyl coenzyme A decarboxylase, malonyl-CoA carboxy-lyase

Taxonomic Range: Metazoa

Standard Gibbs Free Energy (ΔrG in kcal/mol): -1.779419Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Specific for malonyl-CoA. The enzyme from Pseudomonas ovalis also catalyses the reaction of EC malonate CoA-transferase.

Citations: [Buckner76]

Unification Links: KEGG:R00233, Rhea:18781

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:P12617, UniProt:RELATED-TO:Q54112


Buckner76: Buckner JS, Kolattukudy PE, Poulose AJ (1976). "Purification and properties of malonyl-coenzyme A decarboxylase, a regulatory enzyme from the uropygial gland of goose." Arch Biochem Biophys 177(2);539-51. PMID: 827976

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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