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MetaCyc Reaction: 3.5.3.7

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number: 3.5.3.7

Enzymes and Genes:

Arthrobacter sp. KUJ8602: guanidinobutyraseInferred from experiment: gbh
Brevibacterium helvolum: guanidinobutyraseInferred from experiment
Kluyveromyces lactis: guanidinobutyraseInferred from experiment: KlGBU1
Pseudomonas aeruginosa: guanidinobutyraseInferred from experiment: gbuA
Pseudomonas putida: guanidinobutyraseInferred from experiment: gbuA
Streptomyces griseus: guanidinobutyrate amidinohydrolaseInferred from experiment

In Pathway: L-arginine degradation X (arginine monooxygenase pathway), L-arginine degradation VIII (arginine oxidase pathway), L-arginine degradation IX (arginine:pyruvate transaminase pathway), L-arginine degradation XII

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: guanidinobutyrase

Enzyme Commission Synonyms: γ-guanidobutyrase, 4-guanidinobutyrate amidinobutyrase, γ-guanidinobutyrate amidinohydrolase, G-Base, GBH, guanidinobutyrate ureahydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.572998Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires Mn2+. Also acts, very slowly, on 5-guanidinopentanoate and 6-guanidinohexanoate.

Citations: [Mora65, Nguyen66]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R01990, Rhea:19501

Relationship Links: BRENDA:EC:3.5.3.7, ENZYME:EC:3.5.3.7, IUBMB-ExplorEnz:EC:3.5.3.7

Credits:
Revised 05-Sep-2012 by Caspi R, SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Mora65: Mora J, Tarrab R, Martuscelli J, Soberon G (1965). "Characteristics of arginases from ureotelic and non-ureotelic animals." Biochem J 96(3);588-94. PMID: 5862400

Nguyen66: Nguyen Van Thoai , Thome-Beau F, Olomucki A (1966). "[Induction and specificity of enzymes of the new catabolic arginine pathway]." Biochim Biophys Acta 115(1);73-80. PMID: 5936244


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Sun May 1, 2016, biocyc14.