Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 3.5.3.7

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.3.7

Enzymes and Genes:
guanidinobutyrase Inferred from experiment : KlGBU1 ( Kluyveromyces lactis )
guanidinobutyrase Inferred from experiment ( Brevibacterium helvolum )
guanidinobutyrase Inferred from experiment : gbh ( Arthrobacter sp. KUJ8602 )
guanidinobutyrate amidinohydrolase Inferred from experiment ( Streptomyces griseus )
guanidinobutyrase Inferred from experiment : gbuA ( Pseudomonas aeruginosa )
guanidinobutyrase Inferred from experiment : gbuA ( Pseudomonas putida )

In Pathway: arginine degradation X (arginine monooxygenase pathway) , arginine degradation VIII (arginine oxidase pathway) , arginine degradation IX (arginine:pyruvate transaminase pathway) , arginine degradation XII

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: guanidinobutyrase

Enzyme Commission Synonyms: γ-guanidobutyrase, 4-guanidinobutyrate amidinobutyrase, γ-guanidinobutyrate amidinohydrolase, G-Base, GBH, guanidinobutyrate ureahydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.572998 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires Mn2+. Also acts, very slowly, on 5-guanidinopentanoate and 6-guanidinohexanoate.

Citations: [Mora65, Nguyen66]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R01990 , Rhea:19501

Relationship Links: BRENDA:EC:3.5.3.7 , ENZYME:EC:3.5.3.7 , IUBMB-ExplorEnz:EC:3.5.3.7

Credits:
Revised 05-Sep-2012 by Caspi R , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Mora65: Mora J, Tarrab R, Martuscelli J, Soberon G (1965). "Characteristics of arginases from ureotelic and non-ureotelic animals." Biochem J 96(3);588-94. PMID: 5862400

Nguyen66: Nguyen Van Thoai , Thome-Beau F, Olomucki A (1966). "[Induction and specificity of enzymes of the new catabolic arginine pathway]." Biochim Biophys Acta 115(1);73-80. PMID: 5936244


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc14.