Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.5.3.7

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.5.3.7

Enzymes and Genes:
guanidinobutyrase Inferred from experiment : KlGBU1 ( Kluyveromyces lactis )
guanidinobutyrase Inferred from experiment ( Brevibacterium helvolum )
guanidinobutyrase Inferred from experiment : gbh ( Arthrobacter sp. KUJ8602 )
guanidinobutyrate amidinohydrolase Inferred from experiment ( Streptomyces griseus )
guanidinobutyrase Inferred from experiment : gbuA ( Pseudomonas aeruginosa )
guanidinobutyrase Inferred from experiment : gbuA ( Pseudomonas putida )

In Pathway: arginine degradation X (arginine monooxygenase pathway) , arginine degradation VIII (arginine oxidase pathway) , arginine degradation IX (arginine:pyruvate transaminase pathway) , arginine degradation XII

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: guanidinobutyrase

Enzyme Commission Synonyms: γ-guanidobutyrase, 4-guanidinobutyrate amidinobutyrase, γ-guanidinobutyrate amidinohydrolase, G-Base, GBH, guanidinobutyrate ureahydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -3.572998 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires Mn2+. Also acts, very slowly, on 5-guanidinopentanoate and 6-guanidinohexanoate.

Citations: [Mora65, Nguyen66]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R01990 , Rhea:19501

Relationship Links: BRENDA:EC:3.5.3.7 , ENZYME:EC:3.5.3.7 , IUBMB-ExplorEnz:EC:3.5.3.7

Credits:
Revised 05-Sep-2012 by Caspi R , SRI International


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Mora65: Mora J, Tarrab R, Martuscelli J, Soberon G (1965). "Characteristics of arginases from ureotelic and non-ureotelic animals." Biochem J 96(3);588-94. PMID: 5862400

Nguyen66: Nguyen Van Thoai , Thome-Beau F, Olomucki A (1966). "[Induction and specificity of enzymes of the new catabolic arginine pathway]." Biochim Biophys Acta 115(1);73-80. PMID: 5936244


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Nov 28, 2014, biocyc14.