MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:
glyoxylate carboligase Inferred from experiment : gcl ( Escherichia coli K-12 substr. MG1655 )

In Pathway: glycolate and glyoxylate degradation I

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: tartronate-semialdehyde synthase

Enzyme Commission Synonyms: tartronate semialdehyde carboxylase, glyoxylate carbo-ligase, glyoxylic carbo-ligase, hydroxymalonic semialdehyde carboxylase, tartronic semialdehyde carboxylase, glyoxalate carboligase, glyoxylate carboxy-lyase (dimerizing), glyoxylate carboxy-lyase (dimerizing, tartronate-semialdehyde-forming)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -8.025879 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
A flavoprotein.

Citations: [Gupta64a, BARKULIS56]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R00013 , Rhea:10136

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:P0AEP7


BARKULIS56: BARKULIS SS, KRAKOW G (1956). "Conversion of glyoxylate to hydroxypyruvate by extracts of Escherichia coli." Biochim Biophys Acta 21(3);593-4. PMID: 13363977

Gupta64a: Gupta NK, Vennesland B (1964). "Glyoxylate carboligase of Escherichia coli: a flavoprotein." J Biol Chem 239;3787-9. PMID: 14257608

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Wed Apr 1, 2015, BIOCYC14B.