Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 2.3.1.13

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.13

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glycine N-acyltransferase

Enzyme Commission Synonyms: glycine acyltransferase, glycine-N-acylase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 290.23016 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
The CoA derivatives of a number of aliphatic and aromatic acids, but not phenylacetyl-CoA or (indol-3-yl)acetyl-CoA, can act as donor. Not identical with EC 2.3.1.68 glutamine N-acyltransferase or EC 2.3.1.71 glycine N-benzoyltransferase.

Citations: [Webster76, Schachter54, Nandi79]

Unification Links: KEGG:R00395 , Rhea:19872

Relationship Links: BRENDA:EC:2.3.1.13 , ENZYME:EC:2.3.1.13 , IUBMB-ExplorEnz:EC:2.3.1.13


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Nandi79: Nandi DL, Lucas SV, Webster LT (1979). "Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization." J Biol Chem 254(15);7230-7. PMID: 457678

Schachter54: Schachter D, Taggart JV (1954). "Glycine N-acylase: purification and properties." J Biol Chem 208(1);263-75. PMID: 13174534

Webster76: Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ (1976). "Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man." J Biol Chem 251(11);3352-8. PMID: 931988


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Tue Nov 25, 2014, biocyc13.