Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 2.3.1.35

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 2.3.1.35

Enzymes and Genes:
acetylornithine acetyltransferase : ECM40 ( Saccharomyces cerevisiae )
ornithine acetyltransferase Inferred from experiment : argJ ( Bacillus subtilis )

In Pathway: arginine biosynthesis II (acetyl cycle)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: glutamate N-acetyltransferase

Enzyme Commission Synonyms: ornithine transacetylase, α-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase, acetylglutamate synθse, acetylglutamate-acetylornithine transacetylase, acetylglutamic synθse, acetylglutamic-acetylornithine transacetylase, acetylornithinase, acetylornithine glutamate acetyltransferase, glutamate acetyltransferase, N-acetyl-L-glutamate synθse, N-acetylglutamate synthase, N-acetylglutamate synθse, ornithine acetyltransferase, 2-N-acetyl-L-ornithine:L-glutamate N-acetyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -1.2482033 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity.

Citations: [Staub66]

Gene-Reaction Schematic: ?

Unification Links: KEGG:R02282 , Rhea:15349

Relationship Links: BRENDA:EC:2.3.1.35 , ENZYME:EC:2.3.1.35 , IUBMB-ExplorEnz:EC:2.3.1.35 , UniProt:RELATED-TO:P38434 , UniProt:RELATED-TO:P74122 , UniProt:RELATED-TO:Q04728 , UniProt:RELATED-TO:Q07908 , UniProt:RELATED-TO:Q57645


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Staub66: Staub M, Denes G (1966). "Mechanism of arginine biosynthesis in Chlamydomonas reinhardti. I. Purification and properties of ornithine acetyltransferase." Biochim Biophys Acta 128(1);82-91. PMID: 5972370


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc11.