|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
Enzymes and Genes:
|Aggregatibacter actinomycetemcomitans:||GDP-4-keto-6-deoxy-D-mannose reductase: tld|
In Pathway: GDP-6-deoxy-D-talose biosynthesis
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name for 188.8.131.52: GDP-6-deoxy-D-talose 4-dehydrogenase
Enzyme Commission Synonyms for 184.108.40.206: guanosine diphospho-6-deoxy-D-talose dehydrogenase, GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase
Enzyme Commission Primary Name for 220.127.116.11: GDP-4-dehydro-D-rhamnose reductase
Enzyme Commission Synonyms for 18.104.22.168: GDP-4-keto-6-deoxy-D-mannose reductase, GDP-4-keto-D-rhamnose reductase, guanosine diphosphate-4-keto-D-rhamnose reductase, GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase, GDP-6-deoxy-α-D-mannose:NAD(P)+ 4-oxidoreductase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -10.649292 [Latendresse13]
Enzyme Commission Summary for 22.214.171.124:
The enzyme, which operates in the opposite direction to that shown, forms a mixture of GDP-α-D-rhamnose and its C-4 epimer, GDP-6-deoxy-α-D-talose. cf. EC 126.96.36.1991, GDP-4-dehydro-6-deoxy-D-mannose reductase and EC 188.8.131.52, GDP-6-deoxy-D-talose 4-dehydrogenase.
Unification Links: KEGG:R03398
Relationship Links: BRENDA:EC:184.108.40.206, BRENDA:EC:220.127.116.11, ENZYME:EC:18.104.22.168, ENZYME:EC:22.214.171.124, IUBMB-ExplorEnz:EC:126.96.36.199, IUBMB-ExplorEnz:EC:188.8.131.52, Rhea:RELATED-TO:10727, Rhea:RELATED-TO:10731
Markovitz64a: Markovitz A (1964). "Biosynthesis of guanosine diphosphate D-rhamnose and guanosine diphosphate D-talomethylose from guanosine diphosphate alpha-D-mannose." J Biol Chem 239;2091-8. PMID: 14209931
©2015 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493