|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 220.127.116.11
Enzymes and Genes:
1-aminocyclopropane-1-carboxylate oxidase : PAE12 ( Malus domestica )
1-aminocyclopropane-1-carboxylate oxidase : ACO ( Cucumis melo )
aminocyclopropane-1-carboxylate oxidase : ACO4 ( Solanum lycopersicum )
In Pathway: ethylene biosynthesis I (plants)
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: aminocyclopropanecarboxylate oxidase
Enzyme Commission Synonyms: ACC oxidase, ethylene-forming enzyme
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -69.29988 [Latendresse13]
Enzyme Commission Summary:
A nonheme iron enzyme. Requires CO2 for activity. In the enzyme from plants, the ethylene has signalling functions such as stimulation of fruit-ripening.
Zhang95a: Zhang Z, Schofield CJ, Baldwin JE, Thomas P, John P (1995). "Expression, purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from tomato in Escherichia coli." Biochem J 307 ( Pt 1);77-85. PMID: 7717997
Zhang97a: Zhang Z, Barlow JN, Baldwin JE, Schofield CJ (1997). "Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase." Biochemistry 36(50);15999-6007. PMID: 9398335
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