MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Adiantum capillus-veneris: cycloartenol synthaseInferred from experiment: ACX
Arabidopsis thaliana col: cycloartenol synthaseInferred from experiment: CAS1
Avena strigosa: cycloartenol synthaseInferred from experiment: cs1
Kandelia candel: cycloartenol synthaseInferred from experiment: KcCAS
Oryza sativa Japonica Group: cycloartenol synthaseInferred from experiment: LOC_Os02g04710
Panax ginseng: cycloartenol synthaseInferred from experiment: OSCPNX1
Rhizophora stylosa: cycloartenol synthaseInferred from experiment: RcCAS

In Pathway: diploterol and cycloartenol biosynthesis, mangrove triterpenoid biosynthesis, plant sterol biosynthesis, ergosterol biosynthesis II, 7-dehydroporiferasterol biosynthesis, avenacin biosynthesis, initial reactions

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: cycloartenol synthase

Enzyme Commission Synonyms: 2,3-epoxysqualene cycloartenol-cyclase, squalene-2,3-epoxide-cycloartenol cyclase, 2,3-epoxysqualene-cycloartenol cyclase, 2,3-oxidosqualene-cycloartenol cyclase, (S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -92.25006Inferred by computational analysis [Latendresse13]

Citations: [Rees69]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R03200, Rhea:21311

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:O23909


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Rees69: Rees HH, Goad LJ, Goodwin TW (1969). "2,3-oxidosqualene cycloartenol cyclase from Ochromonas malhamensis." Biochim Biophys Acta 176(4);892-4. PMID: 5797101

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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