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MetaCyc Reaction: 5.4.99.8

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 5.4.99.8

Enzymes and Genes:

Adiantum capillus-veneris : cycloartenol synthase Inferred from experiment : ACX
Arabidopsis thaliana col : cycloartenol synthase Inferred from experiment : CAS1
Avena strigosa : cycloartenol synthase Inferred from experiment : cs1
Kandelia candel : cycloartenol synthase Inferred from experiment : KcCAS
Oryza sativa Japonica Group : cycloartenol synthase Inferred from experiment : LOC_Os02g04710
Panax ginseng : cycloartenol synthase Inferred from experiment : OSCPNX1
Rhizophora stylosa : cycloartenol synthase Inferred from experiment : RcCAS

In Pathway: diploterol and cycloartenol biosynthesis , mangrove triterpenoid biosynthesis , plant sterol biosynthesis , ergosterol biosynthesis II , 7-dehydroporiferasterol biosynthesis , avenacin biosynthesis, initial reactions

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: cycloartenol synthase

Enzyme Commission Synonyms: 2,3-epoxysqualene cycloartenol-cyclase, squalene-2,3-epoxide-cycloartenol cyclase, 2,3-epoxysqualene-cycloartenol cyclase, 2,3-oxidosqualene-cycloartenol cyclase, (S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -92.909996 Inferred by computational analysis [Latendresse13]

Citations: [Rees69]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R03200 , Rhea:21311

Relationship Links: BRENDA:EC:5.4.99.8 , ENZYME:EC:5.4.99.8 , IUBMB-ExplorEnz:EC:5.4.99.8 , UniProt:RELATED-TO:O23909


References

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Rees69: Rees HH, Goad LJ, Goodwin TW (1969). "2,3-oxidosqualene cycloartenol cyclase from Ochromonas malhamensis." Biochim Biophys Acta 176(4);892-4. PMID: 5797101


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Mon May 25, 2015, biocyc11.