|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Chlamydomonas reinhardtii:||alcohol dehydrogenase / acetaldehyde dehydrogenase: ADH1|
|Clostridium acetobutylicum ATCC 824:||alcohol/aldehyde dehydrogenase: adhE|
|Corynebacterium glutamicum ATCC 13032:|
|Escherichia coli K-12 substr. MG1655:|
|Glycine max:||alcohol dehydrogenase|
|Homo sapiens:||alcohol dehydrogenase 2: ADH1B|
|Mycobacterium tuberculosis H37Rv:||alcohol dehydrogenase: adhE|
|Nicotiana tabacum:||alcohol dehydrogenase: ADH2|
|Pelobacter acetylenicus:||alcohol dehydrogenase|
|Pisum sativum:||alcohol dehydrogenase: adh|
|Ralstonia eutropha JMP134:||furfuryl alcohol dehydrogenase: furX|
|Solanum tuberosum:||alcohol dehydrogenase: ADH1|
|Streptococcus mutans:||NAD-dependent alcohol dehydrogenase: adhE|
|Zea mays:||alcohol dehydrogenase: ADH1|
In Pathway: ethanol degradation I, ethanol degradation II, pyruvate fermentation to ethanol I, pyruvate fermentation to ethanol II, acetylene degradation, mixed acid fermentation, pyruvate fermentation to ethanol III, superpathway of fermentation (Chlamydomonas reinhardtii), chitin degradation to ethanol, heterolactic fermentation, acetaldehyde biosynthesis I
The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Direct generic reaction:
a primary alcohol + NAD+ ↔ an aldehyde + NADH + H+ (22.214.171.124)
Enzyme Commission Primary Name: alcohol dehydrogenase
Enzyme Commission Synonyms: aldehyde reductase, ADH, alcohol dehydrogenase (NAD), aliphatic alcohol dehydrogenase, ethanol dehydrogenase, NAD-dependent alcohol dehydrogenase, NAD-specific aromatic alcohol dehydrogenase, NADH-alcohol dehydrogenase, NADH-aldehyde dehydrogenase, primary alcohol dehydrogenase, yeast alcohol dehydrogenase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 3.1017761 [Latendresse13]
Enzyme Commission Summary:
A zinc protein. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
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