Enzymes and Genes:
ethanol degradation I
ethanol degradation II
pyruvate fermentation to ethanol I
pyruvate fermentation to ethanol II
mixed acid fermentation
acetaldehyde biosynthesis I
pyruvate fermentation to ethanol III
superpathway of fermentation (Chlamydomonas reinhardtii)
chitin degradation to ethanol
Note that this reaction equation differs from the official Enzyme Commission reaction equations for this EC
number, which can be found
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some
reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB
Concepts Guide for more information.
Mass balance status: Balanced.
Direct generic reaction:
a primary alcohol + NAD+ ↔ an aldehyde + NADH + H+ (184.108.40.206)
Enzyme Commission Primary Name:
Enzyme Commission Synonyms:
alcohol dehydrogenase (NAD),
aliphatic alcohol dehydrogenase,
NAD-dependent alcohol dehydrogenase,
NAD-specific aromatic alcohol dehydrogenase,
primary alcohol dehydrogenase,
yeast alcohol dehydrogenase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol):
Enzyme Commission Summary:
A zinc protein. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol. The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.
Citations: [Jornvall77a, THEORELL58]
Jornvall77a: Jornvall H (1977). "Differences between alcohol dehydrogenases. Structural properties and evolutionary aspects." Eur J Biochem 72(3);443-52. PMID: 320001
Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."
THEORELL58: THEORELL H (1958). "Kinetics and equilibria in the liver alcohol dehydrogenase system." Adv Enzymol Relat Subj Biochem 20;31-49. PMID: 13605979
Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 13, 2015, biocyc13.