MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number:

Enzymes and Genes:

Arabidopsis thaliana col : 4-coumarate coenzyme A ligase 3 Inferred from experiment : 4CL3
4-coumarate coenzyme A ligase 1 Inferred from experiment : 4CL1
Sphingomonas sp. SYK6 : feruloyl-CoA synthetase Inferred from experiment : ferA

In Pathway: ferulate degradation , suberin monomers biosynthesis

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: trans-feruloyl-CoA synthase

Enzyme Commission Synonyms: trans-feruloyl-CoA synθse, trans-ferulate:CoASH ligase (ATP-hydrolysing), ferulate:CoASH ligase (ATP-hydrolysing)

Standard Gibbs Free Energy (ΔrG in kcal/mol): -12.711792 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Requires Mg2+. It has not yet been established whether AMP + diphosphate or ADP + phosphate are formed in this reaction [Narbad98].

Citations: [Pometto83]

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

Unification Links: KEGG:R02194

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Narbad98: Narbad A, Gasson MJ (1998). "Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly-isolated strain of Pseudomonas fluorescens." Microbiology 144 ( Pt 5);1397-405. PMID: 9611814

Pometto83: Pometto AL, Crawford DL (1983). "Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus." Appl Environ Microbiol 45(5);1582-5. PMID: 6870241

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Wed Oct 7, 2015, biocyc14.