|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
feruloyl-CoA synthetase : ferA ( Sphingomonas sp. SYK6 )
4-coumarate coenzyme A ligase 1 : 4CL1 ( Arabidopsis thaliana col )
4-coumarate coenzyme A ligase 3 : 4CL3 ( Arabidopsis thaliana col )
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: trans-feruloyl-CoA synthase
Enzyme Commission Synonyms: trans-feruloyl-CoA synθse, trans-ferulate:CoASH ligase (ATP-hydrolysing), ferulate:CoASH ligase (ATP-hydrolysing)
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -12.711792 [Latendresse13]
Enzyme Commission Summary:
Requires Mg2+. It has not yet been established whether AMP + diphosphate or ADP + phosphate are formed in this reaction [Narbad98].
Unification Links: KEGG:R02194
Narbad98: Narbad A, Gasson MJ (1998). "Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly-isolated strain of Pseudomonas fluorescens." Microbiology 144 ( Pt 5);1397-405. PMID: 9611814
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