|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
Enzymes and Genes:
|Foeniculum vulgare :||(-)-endo-fenchol cyclase
|Ocimum basilicum :||monoterpene synthase
Supersedes EC number: 22.214.171.124
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
Mass balance status: Balanced.
Enzyme Commission Primary Name: (-)-endo-fenchol synthase
Enzyme Commission Synonyms: (-)-endo-fenchol cyclase, geranyl pyrophosphate:(-)-endo-fenchol cyclase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -58.642975 [Latendresse13]
Enzyme Commission Summary:
(3R)-linalyl diphosphate is an intermediate in the reaction.
Croteau88: Croteau R, Satterwhite DM, Wheeler CJ, Felton NM (1988). "Biosynthesis of monoterpenes. Stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (-)-endo-fenchol." J Biol Chem 263(30);15449-53. PMID: 3170591
Croteau89: Croteau R, Miyazaki JH, Wheeler CJ (1989). "Monoterpene biosynthesis: mechanistic evaluation of the geranyl pyrophosphate:(-)-endo-fenchol cyclase from fennel (Foeniculum vulgare)." Arch Biochem Biophys 269(2);507-16. PMID: 2919880
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