MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Foeniculum vulgare: (-)-endo-fenchol cyclaseInferred from experiment
(-)-endo-fenchol cyclaseInferred from experiment
Ocimum basilicum: monoterpene synthaseInferred from experiment: FES

In Pathway: fenchol biosynthesis I, fenchone biosynthesis, fenchol biosynthesis II

Supersedes EC number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Mass balance status: Balanced.

Enzyme Commission Primary Name: (-)-endo-fenchol synthase

Enzyme Commission Synonyms: (-)-endo-fenchol cyclase, geranyl pyrophosphate:(-)-endo-fenchol cyclase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -58.642975Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
(3R)-linalyl diphosphate is an intermediate in the reaction.

Citations: [Croteau88, Croteau89]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R02004, Rhea:20565

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Croteau88: Croteau R, Satterwhite DM, Wheeler CJ, Felton NM (1988). "Biosynthesis of monoterpenes. Stereochemistry of the enzymatic cyclization of geranyl pyrophosphate to (-)-endo-fenchol." J Biol Chem 263(30);15449-53. PMID: 3170591

Croteau89: Croteau R, Miyazaki JH, Wheeler CJ (1989). "Monoterpene biosynthesis: mechanistic evaluation of the geranyl pyrophosphate:(-)-endo-fenchol cyclase from fennel (Foeniculum vulgare)." Arch Biochem Biophys 269(2);507-16. PMID: 2919880

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Tue Dec 1, 2015, BIOCYC13A.