|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions → Transport Energised by P-P Bond Hydrolysis|
|Reactions Classified By Conversion Type → Simple Reactions → Transport Reactions → Transport Energised by P-P Bond Hydrolysis|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
Reaction Locations: extracellular space/cytosol
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balance undetermined; a substrate lacks a chemical formula
Enzyme Commission Primary Name: polar-amino-acid-transporting ATPase
Enzyme Commission Synonyms: histidine permease
Enzyme Commission Summary:
ABC-type (ATP-binding cassette-type) ATPase, characterised by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. Comprises bacterial enzymes that import His, Arg, Lys, Glu, Gln, Asp, ornithine, octopine and nopaline.
Kuan95: Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases." Res Microbiol 146(4);271-8. PMID: 7569321
Nikaido97: Nikaido K, Liu PQ, Ames GF (1997). "Purification and characterization of HisP, the ATP-binding subunit of a traffic ATPase (ABC transporter), the histidine permease of Salmonella typhimurium. Solubility, dimerization, and ATPase activity." J Biol Chem 272(44);27745-52. PMID: 9346917
Walshaw97: Walshaw DL, Lowthorpe S, East A, Poole PS (1997). "Distribution of a sub-class of bacterial ABC polar amino acid transporter and identification of an N-terminal region involved in solute specificity." FEBS Lett 414(2);397-401. PMID: 9315727
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