|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 126.96.36.199
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Mass balance status: Balanced.
Enzyme Commission Primary Name: aliphatic nitrilase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): 1.1898727 [Latendresse13]
Enzyme Commission Summary:
Preferentially hydrolyses aliphatic nitriles, some of which are apparently not substrates for other known nitrilases (EC 188.8.131.52). Substrates include crotononitrile, acrylonitrile and glutaronitrile.
Kobayashi92a: Kobayashi M, Yanaka N, Nagasawa T, Yamada H (1992). "Primary structure of an aliphatic nitrile-degrading enzyme, aliphatic nitrilase, from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residue." Biochemistry 1992;31(37);9000-7. PMID: 1390687
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