Metabolic Modeling Tutorial
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BioCyc websites down
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 3.4.11.21

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.4.11.21

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: aspartyl aminopeptidase

Enzyme Commission Summary:
Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate. Aminoacyl-arylamides are poor substrates. This is an abundant cytosolic enzyme in mammalian cells, in peptidase family M18 of aminopeptidase I

Citations: [Kelly83, Wilk98]

Relationship Links: BRENDA:EC:3.4.11.21 , ENZYME:EC:3.4.11.21 , IUBMB-ExplorEnz:EC:3.4.11.21


References

Kelly83: Kelly JA, Neidle EL, Neidle A (1983). "An aminopeptidase from mouse brain cytosol that cleaves N-terminal acidic amino acid residues." J Neurochem 40(6);1727-34. PMID: 6854330

Wilk98: Wilk S, Wilk E, Magnusson RP (1998). "Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase." J Biol Chem 273(26);15961-70. PMID: 9632644


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Fri Dec 19, 2014, biocyc12.