Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.4.11.14

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.4.11.14

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: cytosol alanyl aminopeptidase

Enzyme Commission Synonyms: arylamidase, aminopolypeptidase, thiol-activated aminopeptidase, human liver aminopeptidase, puromycin-sensitive aminopeptidase, soluble alanyl aminopeptidase, cytosol aminopeptidase III, alanine aminopeptidase

Enzyme Commission Summary:
This enzyme catalyzes release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.

A puromycin-sensitive, Co2+-activated zinc-sialoglycoprotein that is generally cytosolic. Multiple forms are widely distributed in mammalian tissues and body fluids. In peptidase family M1 (membrane alanyl aminopeptidase family).

Citations: [Starnes74, Kao78, Sidorowicz80]

Relationship Links: BRENDA:EC:3.4.11.14 , ENZYME:EC:3.4.11.14 , IUBMB-ExplorEnz:EC:3.4.11.14


References

Kao78: Kao YJ, Starnes WL, Behal FJ (1978). "Human kidney alanine aminopeptidase: physical and kinetic properties of a sialic acid containing glycoprotein." Biochemistry 17(15);2990-4. PMID: 698181

Sidorowicz80: Sidorowicz W, Hsia WC, Maslej-Zownir O, Behal FJ (1980). "Multiple molecular forms of human alanine aminopeptidase: immunochemical properties." Clin Chim Acta 107(3);245-56. PMID: 6108169

Starnes74: Starnes WL, Behal FJ (1974). "A human liver aminopeptidase. The amino acid and carbohydrate content, and some physical properties of a sialic acid containing glycoprotein." Biochemistry 13(16);3221-7. PMID: 4841062


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 20, 2014, biocyc13.