Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Reaction: 3.2.1.103

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.2.1.103

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: keratan-sulfate endo-1,4-β-galactosidase

Enzyme Commission Synonyms: endo-β-galactosidase, keratan sulfate endogalactosidase, keratanase, keratan-sulfate 1,4-β-D-galactanohydrolase

Enzyme Commission Summary:
This enzyme catalyzes endohydrolysis of (1→4)-β-D-galactosidic linkages in keratan sulfate .

Hydrolyses the 1,4-β-D-galactosyl linkages adjacent to 1,3-N-acetyl-α-D-glucosaminyl residues. Also acts on some non-sulfated oligosaccharides, but only acts on blood group substances when the 1,2-linked fucosyl residues have been removed (cf. EC 3.2.1.102, blood-group-substance endo-1,4-β-galactosidase).

Citations: [Fukuda76]

Relationship Links: BRENDA:EC:3.2.1.103 , ENZYME:EC:3.2.1.103 , IUBMB-ExplorEnz:EC:3.2.1.103

Credits:
Revised 26-Jul-2012 by Caspi R , SRI International


References

Fukuda76: Fukuda MN, Matsumura G (1976). "Endo-beta-galactosidase of Escherichia freundii. Purification and endoglycosidic action on keratan sulfates, oligosaccharides, and blood group active glycoprotein." J Biol Chem 251(20);6218-25. PMID: 135762


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Thu Nov 27, 2014, biocyc13.