Metabolic Modeling Tutorial
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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
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for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
BioCyc websites down
12/28 - 12/31
for maintenance.
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MetaCyc Reaction: 3.2.1.103

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions
Reactions Classified By Substrate Small-Molecule Reactions

EC Number: 3.2.1.103

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.

Mass balance status: Undetermined; a substrate lacks a chemical formula

Enzyme Commission Primary Name: keratan-sulfate endo-1,4-β-galactosidase

Enzyme Commission Synonyms: endo-β-galactosidase, keratan sulfate endogalactosidase, keratanase, keratan-sulfate 1,4-β-D-galactanohydrolase

Enzyme Commission Summary:
This enzyme catalyzes endohydrolysis of (1→4)-β-D-galactosidic linkages in keratan sulfate .

Hydrolyses the 1,4-β-D-galactosyl linkages adjacent to 1,3-N-acetyl-α-D-glucosaminyl residues. Also acts on some non-sulfated oligosaccharides, but only acts on blood group substances when the 1,2-linked fucosyl residues have been removed (cf. EC 3.2.1.102, blood-group-substance endo-1,4-β-galactosidase).

Citations: [Fukuda76]

Relationship Links: BRENDA:EC:3.2.1.103 , ENZYME:EC:3.2.1.103 , IUBMB-ExplorEnz:EC:3.2.1.103

Credits:
Revised 26-Jul-2012 by Caspi R , SRI International


References

Fukuda76: Fukuda MN, Matsumura G (1976). "Endo-beta-galactosidase of Escherichia freundii. Purification and endoglycosidic action on keratan sulfates, oligosaccharides, and blood group active glycoprotein." J Biol Chem 251(20);6218-25. PMID: 135762


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Dec 21, 2014, biocyc14.