MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical ReactionsProtein-Modification Reactions
Reactions Classified By SubstrateMacromolecule ReactionsProtein-ReactionsProtein-Modification Reactions

EC Number:

In Pathway: oleate biosynthesis I (plants)

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: oleoyl-[acyl-carrier-protein] hydrolase

Enzyme Commission Synonyms: acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, oleoyl-acyl carrier protein thioesterase, oleoyl-[acyl-carrier-protein] hydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 322.2987Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Acts on acyl-carrier-protein thioesters of fatty acids from C12 to C18, but the derivative of oleic acid is hydrolysed much more rapidly than any other compound tested.

Citations: [Ohlrogge78, Shine76]

Unification Links: KEGG:R02814

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:, UniProt:RELATED-TO:O48568, UniProt:RELATED-TO:O49947, UniProt:RELATED-TO:P00633, UniProt:RELATED-TO:P08635, UniProt:RELATED-TO:P12276, UniProt:RELATED-TO:P12785, UniProt:RELATED-TO:P19829, UniProt:RELATED-TO:P49327, UniProt:RELATED-TO:Q9SV64, UniProt:RELATED-TO:Q39402, UniProt:RELATED-TO:Q41635, UniProt:RELATED-TO:Q42558, UniProt:RELATED-TO:Q42561, UniProt:RELATED-TO:Q43718, UniProt:RELATED-TO:Q43745

Revised 12-Dec-2011 by Caspi R, SRI International


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Ohlrogge78: Ohlrogge JB, Shine WE, Stumpf PK (1978). "Fat metabolism in higher plants. Characterization of plant acyl-ACP and acyl-CoA hydrolases." Arch Biochem Biophys 189(2);382-91. PMID: 30409

Shine76: Shine WE, Mancha M, Stumpf PK (1976). "Fat metabolism in higher plants. The function of acyl thioesterases in the metabolism of acyl-coenzymes A and acyl-acyl carrier proteins." Arch Biochem Biophys 172(1);110-6. PMID: 3134

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by Pathway Tools version 19.5 (software by SRI International) on Tue Nov 24, 2015, biocyc13.