MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion Type Simple Reactions Chemical Reactions Protein-Modification Reactions
Reactions Classified By Substrate Macromolecule Reactions Protein-Reactions Protein-Modification Reactions

EC Number:

In Pathway: oleate biosynthesis I (plants)

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: oleoyl-[acyl-carrier-protein] hydrolase

Enzyme Commission Synonyms: acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, oleoyl-acyl carrier protein thioesterase, oleoyl-[acyl-carrier-protein] hydrolase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 322.2987 Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Acts on acyl-carrier-protein thioesters of fatty acids from C12 to C18, but the derivative of oleic acid is hydrolysed much more rapidly than any other compound tested.

Citations: [Ohlrogge78, Shine76]

Relationship Links: BRENDA:EC: , ENZYME:EC: , IUBMB-ExplorEnz:EC: , UniProt:RELATED-TO:O48568 , UniProt:RELATED-TO:O49947 , UniProt:RELATED-TO:P00633 , UniProt:RELATED-TO:P08635 , UniProt:RELATED-TO:P12276 , UniProt:RELATED-TO:P12785 , UniProt:RELATED-TO:P19829 , UniProt:RELATED-TO:P49327 , UniProt:RELATED-TO:Q9SV64 , UniProt:RELATED-TO:Q39402 , UniProt:RELATED-TO:Q41635 , UniProt:RELATED-TO:Q42558 , UniProt:RELATED-TO:Q42561 , UniProt:RELATED-TO:Q43718 , UniProt:RELATED-TO:Q43745

Revised 12-Dec-2011 by Caspi R , SRI International


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Ohlrogge78: Ohlrogge JB, Shine WE, Stumpf PK (1978). "Fat metabolism in higher plants. Characterization of plant acyl-ACP and acyl-CoA hydrolases." Arch Biochem Biophys 189(2);382-91. PMID: 30409

Shine76: Shine WE, Mancha M, Stumpf PK (1976). "Fat metabolism in higher plants. The function of acyl thioesterases in the metabolism of acyl-coenzymes A and acyl-acyl carrier proteins." Arch Biochem Biophys 172(1);110-6. PMID: 3134

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.0 on Tue Oct 6, 2015, biocyc12.