MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Mass balance status: Balanced.

Enzyme Commission Primary Name: 1-alkyl-2-acetylglycerol O-acyltransferase

Enzyme Commission Synonyms: 1-hexadecyl-2-acetylglycerol acyltransferase

Standard Gibbs Free Energy (ΔrG in kcal/mol): 325.0658Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
A number of acyl-CoAs can act as acyl donor; maximum activity is obtained with linoleoyl-CoA. Not identical with EC diacylglycerol O-acyltransferase.

Citations: [Kawasaki88]

Unification Links: KEGG:R04363, Rhea:21996

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Kawasaki88: Kawasaki T, Snyder F (1988). "Synthesis of a novel acetylated neutral lipid related to platelet-activating factor by acyl-CoA:1-O-alkyl-2-acetyl-sn-glycerol acyltransferase in HL-60 cells." J Biol Chem 263(6);2593-6. PMID: 3422635

Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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