|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
In Pathway: fructose degradation
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: 1-phosphofructokinase
Enzyme Commission Synonyms: fructose-1-phosphate kinase, 1-phosphofructokinase (phosphorylating), D-fructose-1-phosphate kinase, fructose 1-phosphate kinase, phosphofructokinase 1
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -12.222412 [Latendresse13]
Enzyme Commission Summary:
ITP, GTP or UTP can replace ATP.
Relationship Links: BRENDA:EC:22.214.171.124 , ENZYME:EC:126.96.36.199 , IUBMB-ExplorEnz:EC:188.8.131.52 , UniProt:RELATED-TO:P0AEW9 , UniProt:RELATED-TO:P23354 , UniProt:RELATED-TO:P23386 , UniProt:RELATED-TO:P44330 , UniProt:RELATED-TO:P75038 , UniProt:RELATED-TO:Q48996
Sapico69: Sapico V, Anderson RL (1969). "D-fructose 1-phosphate kinase and D-fructose 6-phosphate kinase from Aerobacter aerogenes. A comparative study of regulatory properties." J Biol Chem 244(22);6280-8. PMID: 4242639
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