|Superclasses:||Reactions Classified By Conversion Type → Simple Reactions → Chemical Reactions|
|Reactions Classified By Substrate → Small-Molecule Reactions|
EC Number: 18.104.22.168
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the Enzyme Commission system.
Most BioCyc compounds have been protonated to a reference pH value of 7.3, and some reactions have been computationally balanced for hydrogen by adding free protons. Please see the PGDB Concepts Guide for more information.
Mass balance status: Balanced.
Enzyme Commission Primary Name: aspartate dehydrogenase
Enzyme Commission Synonyms: NAD-dependent aspartate dehydrogenase, NADH2-dependent aspartate dehydrogenase, NADP+-dependent aspartate dehydrogenase
Standard Gibbs Free Energy (ΔrG'° in kcal/mol): -3.2305908 [Latendresse13]
Enzyme Commission Summary:
Catalyzes the first step in NAD biosynthesis from aspartate. Strictly specific for L-aspartate as substrate. Has a higher affinity for NAD(+) than NADP(+).
Unification Links: KEGG:R07165
Yang03b: Yang Z, Savchenko A, Yakunin A, Zhang R, Edwards A, Arrowsmith C, Tong L (2003). "Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643." J Biol Chem 278(10);8804-8. PMID: 12496312
©2014 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493