MetaCyc Reaction:

Superclasses: Reactions Classified By Conversion TypeSimple ReactionsChemical Reactions
Reactions Classified By SubstrateSmall-Molecule Reactions

EC Number:

Enzymes and Genes:

Mus musculus: 3β-hydroxy-Δ5-C27 steroid oxidoreductaseInferred from experiment: Hsd3b7

In Pathway: bile acid biosynthesis, neutral pathway

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the Enzyme Commission system.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name: cholest-5-ene-3β,7α-diol 3β-dehydrogenase

Enzyme Commission Synonyms: 3β-hydroxy-δ5-C27-steroid oxidoreductase

Standard Gibbs Free Energy (ΔrG in kcal/mol): -5.4582367Inferred by computational analysis [Latendresse13]

Enzyme Commission Summary:
Highly specific for 3β-hydroxy-C27-steroids with Δ5-double bond.

Citations: [Wikvall81 ]

Gene-Reaction Schematic

Gene-Reaction Schematic

Unification Links: KEGG:R04263, Rhea:11896

Relationship Links: BRENDA:EC:, ENZYME:EC:, IUBMB-ExplorEnz:EC:


Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."

Wikvall81: Wikvall K (1981). "Purification and properties of a 3 beta-hydroxy-delta 5-C27-steroid oxidoreductase from rabbit liver microsomes." J Biol Chem 256(7);3376-80. PMID: 6937465

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 19.5 on Wed Nov 25, 2015, BIOCYC14A.