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MetaCyc Polypeptide: 50S ribosomal subunit protein L9

Gene: rplI Accession Numbers: EG10870 (MetaCyc), b4203, ECK4199

Species: Escherichia coli K-12 substr. MG1655

Component of:
50S ribosomal subunit
ribosome

Summary:
The L9 protein is a component of the 50S subunit of the ribosome. L9 is universally conserved in eubacteria, but not in other domains of life; surprisingly, it is not essential. L9 appears to be involved in maintenance of the reading frame during translational pauses [Atkins09]. A model for the physiological function of L9 has been proposed [Naganathan15].

L9 is part of the first reconstitution intermediate of the 50S subunit [Herold87, Tumminia94]. L9 can be crosslinked to L2 and L28 [Kakegawa86, Redl89, Walleczek89a] and is exposed on the ribosome surface [Agafonov97]. A solution structure determined by cryo-EM showed that the L9 protein consists of N-terminal and C-terminal domains connected by a long α helical domain that is wrapped around the L1 stalk [Matadeen99]. An atomic model of L9 within the ribosome was obtained in a cryo-EM structure, revealing contacts with the 30S subunit [Fischer15].

The binding region of L9 on domain V of 23S rRNA was mapped [Ostergaard98, Vladimirov00]. The N- and C-terminal domains of L9 interact with two separate sites in domain V of 23S rRNA [Adamski96, Lieberman00]. Crosslinking of tRNA in the A site of the ribosome to L9 depends on the state of the tRNA [Graifer89].

L9 may normally be involved to limit "ribosomal hopping" during translation of bacteriophage T4 gene 60 [Herbst94, Adamski96, Herr00, Herr01]. In a strain lacking rplI, frameshifting, stop-hopping [Herr01], as well as recoding at stalled ribosomes [Seidman11] is increased.

Strains that contain certain mutations in the essential ribosomal stability factor Der are dependent on L9 for survival. The N-terminal domain of L9 is both necessary and sufficient for complementation of the derT57I mutant allele [Naganathan13]. A second class of mutations causing synthetic phenotypes map to EF-P and enzymes responsible for its post-translational modification. L9 improves subunit maturation in der and efp mutant backgrounds [Naganathan15].

An rplI mutant with a temperature-sensitive growth defect has been isolated [Isono78, Isono78a]. An rplI deletion shows only a slight growth defect [Naganathan13].

Review: [Atkins09]

Citations: [Branlant76, Morrison77, Robertson77, Branlant77, Subramanian77, Kitakawa80, Kamp83, Moureau83, StofflerMeilick83, Traut83, Vladimirov85, Abdurashidova85, Schnier86, Osswald90, Nag91, Kuroda01, Sato01, Schuwirth05, Hwang06, Gordiyenko08, Dunkle11, AlMajdoub13]

Locations: cytosol, ribosome

Map Position: [4,424,131 -> 4,424,580]

Molecular Weight of Polypeptide: 15.7 kD (experimental) [Giri79 ]

Unification Links: ASAP:ABE-0013746 , CGSC:257 , DIP:DIP-35748N , EchoBASE:EB0863 , EcoGene:EG10870 , EcoliWiki:b4203 , Mint:MINT-1228834 , ModBase:P0A7R1 , OU-Microarray:b4203 , PortEco:b4203 , PR:PRO_000023815 , Pride:P0A7R1 , Protein Model Portal:P0A7R1 , RefSeq:NP_418624 , RegulonDB:EG10870 , SMR:P0A7R1 , String:511145.b4203 , UniProt:P0A7R1

Relationship Links: InterPro:IN-FAMILY:IPR000244 , InterPro:IN-FAMILY:IPR009027 , InterPro:IN-FAMILY:IPR020069 , InterPro:IN-FAMILY:IPR020070 , InterPro:IN-FAMILY:IPR020594 , Panther:IN-FAMILY:PTHR21368 , PDB:Structure:1P85 , PDB:Structure:1P86 , PDB:Structure:1VS6 , PDB:Structure:1VS8 , PDB:Structure:1VT2 , PDB:Structure:2AW4 , PDB:Structure:2AWB , PDB:Structure:2GYA , PDB:Structure:2GYC , PDB:Structure:2I2T , PDB:Structure:2I2V , PDB:Structure:2J28 , PDB:Structure:2QAM , PDB:Structure:2QAO , PDB:Structure:2QBA , PDB:Structure:2QBC , PDB:Structure:2QBE , PDB:Structure:2QBG , PDB:Structure:2QBI , PDB:Structure:2QBK , PDB:Structure:2QOV , PDB:Structure:2QOX , PDB:Structure:2QOZ , PDB:Structure:2QP1 , PDB:Structure:2RDO , PDB:Structure:2VHM , PDB:Structure:2VHN , PDB:Structure:2WWQ , PDB:Structure:2Z4L , PDB:Structure:2Z4N , PDB:Structure:3BBX , PDB:Structure:3DF2 , PDB:Structure:3DF4 , PDB:Structure:3E1B , PDB:Structure:3E1D , PDB:Structure:3FIK , PDB:Structure:3I1N , PDB:Structure:3I1P , PDB:Structure:3I1R , PDB:Structure:3I1T , PDB:Structure:3I20 , PDB:Structure:3I22 , PDB:Structure:3IZT , PDB:Structure:3IZU , PDB:Structure:3J4X , PDB:Structure:3J01 , PDB:Structure:3J0T , PDB:Structure:3J0W , PDB:Structure:3J0Y , PDB:Structure:3J11 , PDB:Structure:3J12 , PDB:Structure:3J14 , PDB:Structure:3J19 , PDB:Structure:3J37 , PDB:Structure:3J50 , PDB:Structure:3J51 , PDB:Structure:3J52 , PDB:Structure:3J54 , PDB:Structure:3J56 , PDB:Structure:3J58 , PDB:Structure:3J5A , PDB:Structure:3J5C , PDB:Structure:3J5E , PDB:Structure:3J5G , PDB:Structure:3J5I , PDB:Structure:3J5K , PDB:Structure:3J5L , PDB:Structure:3J5O , PDB:Structure:3J5U , PDB:Structure:3J5W , PDB:Structure:3J7Z , PDB:Structure:3KCR , PDB:Structure:3OAS , PDB:Structure:3OAT , PDB:Structure:3OFC , PDB:Structure:3OFD , PDB:Structure:3OFQ , PDB:Structure:3OFR , PDB:Structure:3OFZ , PDB:Structure:3OG0 , PDB:Structure:3ORB , PDB:Structure:3R8S , PDB:Structure:3R8T , PDB:Structure:487D , PDB:Structure:4CSU , PDB:Structure:4GAR , PDB:Structure:4GAU , PDB:Structure:4KIX , PDB:Structure:4KIZ , PDB:Structure:4KJ1 , PDB:Structure:4KJ3 , PDB:Structure:4KJ5 , PDB:Structure:4KJ7 , PDB:Structure:4KJ9 , PDB:Structure:4KJB , PDB:Structure:4PEB , PDB:Structure:4PEC , PDB:Structure:4TOM , PDB:Structure:4TOO , PDB:Structure:4TOV , PDB:Structure:4TOX , PDB:Structure:4TP1 , PDB:Structure:4TP3 , PDB:Structure:4TP5 , PDB:Structure:4TP7 , PDB:Structure:4TP9 , PDB:Structure:4TPB , PDB:Structure:4TPD , PDB:Structure:4TPF , PDB:Structure:4WAP , PDB:Structure:4WAR , Pfam:IN-FAMILY:PF01281 , Pfam:IN-FAMILY:PF03948 , Prosite:IN-FAMILY:PS00651

Ortholog Links: Ecol199310Cyc (Escherichia coli CFT073):C5294 , EcoO157Cyc (Escherichia coli O157:H7 str. EDL933):RPLI , ShigellaCyc (Shigella flexneri 2a str. 2457T):RPLI

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

GO Terms:

Biological Process: GO:0006412 - translation Inferred by computational analysis [Gaudet10, GOA06, GOA01a]
Molecular Function: GO:0070180 - large ribosomal subunit rRNA binding Inferred from experiment [Marquardt79, Adamski96]
GO:0003723 - RNA binding Inferred by computational analysis [UniProtGOA11a]
GO:0003735 - structural constituent of ribosome Inferred by computational analysis [GOA01a]
GO:0019843 - rRNA binding Inferred by computational analysis [UniProtGOA11a, GOA06]
GO:0044822 - poly(A) RNA binding Inferred by computational analysis [Gaudet10]
Cellular Component: GO:0005829 - cytosol Inferred from experiment Inferred by computational analysis [DiazMejia09, Ishihama08, LopezCampistrou05]
GO:0022625 - cytosolic large ribosomal subunit Inferred from experiment [Hindennach71]
GO:0005840 - ribosome Inferred by computational analysis [UniProtGOA11a, GOA01a]
GO:0030529 - ribonucleoprotein complex Inferred by computational analysis [UniProtGOA11a]

MultiFun Terms: cell structure ribosomes
information transfer protein related ribosomal proteins
information transfer protein related translation

Credits:
Last-Curated ? 03-Apr-2006 by Keseler I , SRI International


Subunit of: 50S ribosomal subunit

Synonyms: ribosome, large subunit

Species: Escherichia coli K-12 substr. MG1655

Subunit composition of 50S ribosomal subunit = [RplA][RplB][RplC][RplD][RplE][RplF][(RplJ)([RplL]2)2][RplI][RplJ][RplK][RplM][RplN][RplO][RplP][RplQ][RplR][RplS][RplT][RplU][RplV][RplW][RplX][RplY][RpmA][RpmB][RpmC][RpmD][RpmE][RpmF][RpmG][RpmH][RpmI][RpmJ][5S ribosomal RNA (rrfA)][23S ribosomal RNA (rrlA)]
         50S ribosomal subunit protein L1 = RplA (extended summary available)
         50S ribosomal subunit protein L2 = RplB (summary available)
         50S ribosomal subunit protein L3 = RplC (summary available)
         50S ribosomal subunit protein L4 = RplD (extended summary available)
         50S ribosomal subunit protein L5 = RplE (extended summary available)
         50S ribosomal subunit protein L6 = RplF (summary available)
         50S ribosomal protein complex L8 = (RplJ)([RplL]2)2
                 50S ribosomal subunit protein L10 = RplJ (extended summary available)
                 50S ribosomal subunit protein L7/L12 dimer = (RplL)2
                         50S ribosomal subunit protein L12 = RplL
         50S ribosomal subunit protein L9 = RplI (extended summary available)
         50S ribosomal subunit protein L10 = RplJ (extended summary available)
         50S ribosomal subunit protein L11 = RplK (extended summary available)
         50S ribosomal subunit protein L13 = RplM (extended summary available)
         50S ribosomal subunit protein L14 = RplN (extended summary available)
         50S ribosomal subunit protein L15 = RplO (summary available)
         50S ribosomal subunit protein L16 = RplP (extended summary available)
         50S ribosomal subunit protein L17 = RplQ (summary available)
         50S ribosomal subunit protein L18 = RplR (extended summary available)
         50S ribosomal subunit protein L19 = RplS (extended summary available)
         50S ribosomal subunit protein L20 = RplT (extended summary available)
         50S ribosomal subunit protein L21 = RplU (summary available)
         50S ribosomal subunit protein L22 = RplV (extended summary available)
         50S ribosomal subunit protein L23 = RplW (extended summary available)
         50S ribosomal subunit protein L24 = RplX (summary available)
         50S ribosomal subunit protein L25 = RplY (extended summary available)
         50S ribosomal subunit protein L27 = RpmA (extended summary available)
         50S ribosomal subunit protein L28 = RpmB (summary available)
         50S ribosomal subunit protein L29 = RpmC (summary available)
         50S ribosomal subunit protein L30 = RpmD (summary available)
         50S ribosomal subunit protein L31 = RpmE (summary available)
         50S ribosomal subunit protein L32 = RpmF (summary available)
         50S ribosomal subunit protein L33 = RpmG (summary available)
         50S ribosomal subunit protein L34 = RpmH (summary available)
         50S ribosomal subunit protein L35 = RpmI (summary available)
         50S ribosomal subunit protein L36 = RpmJ (summary available)

Component of: ribosome

Credits:
Created 02-Jun-2006 by Keseler I , SRI International


Subunit of: ribosome

Species: Escherichia coli K-12 substr. MG1655

Subunit composition of ribosome = [(RpsA)(RpsB)(RpsC)(RpsD)(RpsE)(RpsF)(RpsG)(RpsH)(RpsI)(RpsJ)(RpsK)(RpsL)(RpsM)(RpsN)(RpsO)(RpsP)(RpsQ)(RpsR)(RpsS)(RpsT)(RpsU)(Sra)(16S ribosomal RNA (rrsA))][(RplA)(RplB)(RplC)(RplD)(RplE)(RplF)([RplJ][(RplL)2]2)(RplI)(RplJ)(RplK)(RplM)(RplN)(RplO)(RplP)(RplQ)(RplR)(RplS)(RplT)(RplU)(RplV)(RplW)(RplX)(RplY)(RpmA)(RpmB)(RpmC)(RpmD)(RpmE)(RpmF)(RpmG)(RpmH)(RpmI)(RpmJ)(5S ribosomal RNA (rrfA))(23S ribosomal RNA (rrlA))]
         30S ribosomal subunit = (RpsA)(RpsB)(RpsC)(RpsD)(RpsE)(RpsF)(RpsG)(RpsH)(RpsI)(RpsJ)(RpsK)(RpsL)(RpsM)(RpsN)(RpsO)(RpsP)(RpsQ)(RpsR)(RpsS)(RpsT)(RpsU)(Sra)(16S ribosomal RNA (rrsA))
                 30S ribosomal subunit protein S1 = RpsA (extended summary available)
                 30S ribosomal subunit protein S2 = RpsB (summary available)
                 30S ribosomal subunit protein S3 = RpsC (summary available)
                 30S ribosomal subunit protein S4 = RpsD (extended summary available)
                 30S ribosomal subunit protein S5 = RpsE (extended summary available)
                 30S ribosomal subunit protein S6 = RpsF (extended summary available)
                 30S ribosomal subunit protein S7 = RpsG (extended summary available)
                 30S ribosomal subunit protein S8 = RpsH (extended summary available)
                 30S ribosomal subunit protein S9 = RpsI (extended summary available)
                 30S ribosomal subunit protein S10 = RpsJ (extended summary available)
                 30S ribosomal subunit protein S11 = RpsK (summary available)
                 30S ribosomal subunit protein S12 = RpsL (extended summary available)
                 30S ribosomal subunit protein S13 = RpsM (extended summary available)
                 30S ribosomal subunit protein S14 = RpsN (summary available)
                 30S ribosomal subunit protein S15 = RpsO (extended summary available)
                 30S ribosomal subunit protein S16 = RpsP (summary available)
                 30S ribosomal subunit protein S17 = RpsQ (summary available)
                 30S ribosomal subunit protein S18 = RpsR (extended summary available)
                 30S ribosomal subunit protein S19 = RpsS (summary available)
                 30S ribosomal subunit protein S20 = RpsT (extended summary available)
                 30S ribosomal subunit protein S21 = RpsU (summary available)
                 30S ribosomal subunit protein S22 = Sra (summary available)
         50S ribosomal subunit = (RplA)(RplB)(RplC)(RplD)(RplE)(RplF)([RplJ][(RplL)2]2)(RplI)(RplJ)(RplK)(RplM)(RplN)(RplO)(RplP)(RplQ)(RplR)(RplS)(RplT)(RplU)(RplV)(RplW)(RplX)(RplY)(RpmA)(RpmB)(RpmC)(RpmD)(RpmE)(RpmF)(RpmG)(RpmH)(RpmI)(RpmJ)(5S ribosomal RNA (rrfA))(23S ribosomal RNA (rrlA))
                 50S ribosomal subunit protein L1 = RplA (extended summary available)
                 50S ribosomal subunit protein L2 = RplB (summary available)
                 50S ribosomal subunit protein L3 = RplC (summary available)
                 50S ribosomal subunit protein L4 = RplD (extended summary available)
                 50S ribosomal subunit protein L5 = RplE (extended summary available)
                 50S ribosomal subunit protein L6 = RplF (summary available)
                 50S ribosomal protein complex L8 = (RplJ)([RplL]2)2
                         50S ribosomal subunit protein L10 = RplJ (extended summary available)
                         50S ribosomal subunit protein L7/L12 dimer = (RplL)2
                                 50S ribosomal subunit protein L12 = RplL
                 50S ribosomal subunit protein L9 = RplI (extended summary available)
                 50S ribosomal subunit protein L10 = RplJ (extended summary available)
                 50S ribosomal subunit protein L11 = RplK (extended summary available)
                 50S ribosomal subunit protein L13 = RplM (extended summary available)
                 50S ribosomal subunit protein L14 = RplN (extended summary available)
                 50S ribosomal subunit protein L15 = RplO (summary available)
                 50S ribosomal subunit protein L16 = RplP (extended summary available)
                 50S ribosomal subunit protein L17 = RplQ (summary available)
                 50S ribosomal subunit protein L18 = RplR (extended summary available)
                 50S ribosomal subunit protein L19 = RplS (extended summary available)
                 50S ribosomal subunit protein L20 = RplT (extended summary available)
                 50S ribosomal subunit protein L21 = RplU (summary available)
                 50S ribosomal subunit protein L22 = RplV (extended summary available)
                 50S ribosomal subunit protein L23 = RplW (extended summary available)
                 50S ribosomal subunit protein L24 = RplX (summary available)
                 50S ribosomal subunit protein L25 = RplY (extended summary available)
                 50S ribosomal subunit protein L27 = RpmA (extended summary available)
                 50S ribosomal subunit protein L28 = RpmB (summary available)
                 50S ribosomal subunit protein L29 = RpmC (summary available)
                 50S ribosomal subunit protein L30 = RpmD (summary available)
                 50S ribosomal subunit protein L31 = RpmE (summary available)
                 50S ribosomal subunit protein L32 = RpmF (summary available)
                 50S ribosomal subunit protein L33 = RpmG (summary available)
                 50S ribosomal subunit protein L34 = RpmH (summary available)
                 50S ribosomal subunit protein L35 = RpmI (summary available)
                 50S ribosomal subunit protein L36 = RpmJ (summary available)

Credits:
Created 15-Jun-2006 by Keseler I , SRI International


Sequence Features

Feature Class Location Citations Comment
Acetylation-Modification 57
[Yu08]
 
N6-succinyllysine-Modification 71
[Zhang11a, UniProt12]
UniProt: N6-succinyllysine.
N6-succinyllysine-Modification 83
[Zhang11a, UniProt12]
UniProt: N6-succinyllysine.
N6-acetyllysine-Modification 89
[Zhang09a, UniProt15]
UniProt: N6-acetyllysine.
Sequence-Conflict 106
[Kamp82, UniProt15]
UniProt: (in Ref. 1; AA sequence).
N6-succinyllysine-Modification 112
[Zhang11a, UniProt12]
UniProt: N6-succinyllysine.
Sequence-Conflict 125 -> 128
[Kamp82, UniProt15]
UniProt: (in Ref. 1; AA sequence).
Sequence-Conflict 136
[Kamp82, UniProt15]
UniProt: (in Ref. 1; AA sequence).

History:
10/20/97 Gene b4203 from Blattner lab Genbank (v. M52) entry merged into EcoCyc gene EG10870.


References

Abdurashidova85: Abdurashidova GG, Tsvetkova EA, Chernyi AA, Kaminir LB, Budowsky EI (1985). "Intersubunit RNA-protein contacts in pre- and post-translocated E. coli ribosome." FEBS Lett 185(2);291-4. PMID: 2581817

Adamski96: Adamski FM, Atkins JF, Gesteland RF (1996). "Ribosomal protein L9 interactions with 23 S rRNA: the use of a translational bypass assay to study the effect of amino acid substitutions." J Mol Biol 261(3);357-71. PMID: 8780779

Agafonov97: Agafonov DE, Kolb VA, Spirin AS (1997). "Proteins on ribosome surface: measurements of protein exposure by hot tritium bombardment technique." Proc Natl Acad Sci U S A 94(24);12892-7. PMID: 9371771

AlMajdoub13: Al-Majdoub ZM, Owoseni A, Gaskell SJ, Barber J (2013). "Effects of gentamicin on the proteomes of aerobic and oxygen-limited Escherichia coli." J Med Chem 56(7);2904-10. PMID: 23517076

Atkins09: Atkins JF, Bjork GR (2009). "A gripping tale of ribosomal frameshifting: extragenic suppressors of frameshift mutations spotlight P-site realignment." Microbiol Mol Biol Rev 73(1);178-210. PMID: 19258537

Branlant76: Branlant C, Krol A, Sriwidada J, Brimacombe R (1976). "RNA sequences associated with proteins L1, L9, and L5, L18, L25, in ribonucleoprotein fragments isolated from the 50-S subunit of Escherichia coli ribosomes." Eur J Biochem 70(2);483-92. PMID: 827440

Branlant77: Branlant C, Widada JS, Krol A, Ebel JP (1977). "Studies on the primary structure of the ribosomal 23S RNA of Escherichia coli: II. A characterisation and an alignment of 24 sections spanning the entire molecule and its application to the localisation of specific fragments." Nucleic Acids Res 4(12);4323-45. PMID: 414209

DiazMejia09: Diaz-Mejia JJ, Babu M, Emili A (2009). "Computational and experimental approaches to chart the Escherichia coli cell-envelope-associated proteome and interactome." FEMS Microbiol Rev 33(1);66-97. PMID: 19054114

Dunkle11: Dunkle JA, Wang L, Feldman MB, Pulk A, Chen VB, Kapral GJ, Noeske J, Richardson JS, Blanchard SC, Cate JH (2011). "Structures of the bacterial ribosome in classical and hybrid states of tRNA binding." Science 332(6032);981-4. PMID: 21596992

Fischer15: Fischer N, Neumann P, Konevega AL, Bock LV, Ficner R, Rodnina MV, Stark H (2015). "Structure of the E. coli ribosome-EF-Tu complex at <3A resolution by Cs-corrected cryo-EM." Nature 520(7548);567-70. PMID: 25707802

Gaudet10: Gaudet P, Livstone M, Thomas P (2010). "Annotation inferences using phylogenetic trees." PMID: 19578431

Giri79: Giri L, Franz A, Dijk J (1979). "Shapes of proteins L1, L9, L25, and L30 from the 50S subunit of the Escherichia coli ribosome, determined by hydrodynamic studies." Biochemistry 18(12);2520-5. PMID: 375974

GOA01a: GOA, DDB, FB, MGI, ZFIN (2001). "Gene Ontology annotation through association of InterPro records with GO terms."

GOA06: GOA, SIB (2006). "Electronic Gene Ontology annotations created by transferring manual GO annotations between orthologous microbial proteins."

Gordiyenko08: Gordiyenko Y, Deroo S, Zhou M, Videler H, Robinson CV (2008). "Acetylation of L12 increases interactions in the Escherichia coli ribosomal stalk complex." J Mol Biol 380(2);404-14. PMID: 18514735

Graifer89: Graifer DM, Babkina GT, Matasova NB, Vladimirov SN, Karpova GG, Vlassov VV (1989). "Structural arrangement of tRNA binding sites on Escherichia coli ribosomes, as revealed from data on affinity labelling with photoactivatable tRNA derivatives." Biochim Biophys Acta 1008(2);146-56. PMID: 2660905

Herbst94: Herbst KL, Nichols LM, Gesteland RF, Weiss RB (1994). "A mutation in ribosomal protein L9 affects ribosomal hopping during translation of gene 60 from bacteriophage T4." Proc Natl Acad Sci U S A 91(26);12525-9. PMID: 7809071

Herold87: Herold M, Nierhaus KH (1987). "Incorporation of six additional proteins to complete the assembly map of the 50 S subunit from Escherichia coli ribosomes." J Biol Chem 262(18);8826-33. PMID: 3298242

Herr00: Herr AJ, Gesteland RF, Atkins JF (2000). "One protein from two open reading frames: mechanism of a 50 nt translational bypass." EMBO J 19(11);2671-80. PMID: 10835364

Herr01: Herr AJ, Nelson CC, Wills NM, Gesteland RF, Atkins JF (2001). "Analysis of the roles of tRNA structure, ribosomal protein L9, and the bacteriophage T4 gene 60 bypassing signals during ribosome slippage on mRNA." J Mol Biol 309(5);1029-48. PMID: 11399077

Hindennach71: Hindennach I, Kaltschmidt E, Wittmann HG (1971). "Ribosomal proteins. Isolation of proteins from 50S ribosomal subunits of Escherichia coli." Eur J Biochem 23(1);12-6. PMID: 4942547

Hwang06: Hwang J, Inouye M (2006). "The tandem GTPase, Der, is essential for the biogenesis of 50S ribosomal subunits in Escherichia coli." Mol Microbiol 61(6);1660-72. PMID: 16930151

Ishihama08: Ishihama Y, Schmidt T, Rappsilber J, Mann M, Hartl FU, Kerner MJ, Frishman D (2008). "Protein abundance profiling of the Escherichia coli cytosol." BMC Genomics 9;102. PMID: 18304323

Isono78: Isono S, Isono K, Hirota Y (1978). "Mutations affecting the structural genes and the genes coding for modifying enzymes for ribosomal proteins in Escherichia coli." MGG Molecular & General Genetics 165(1);15-20.

Isono78a: Isono K, Kitakawa M (1978). "Cluster of ribosomal protein genes in Escherichia coli containing genes for proteins S6, S18, and L9." Proc Natl Acad Sci U S A 75(12);6163-7. PMID: 366612

Kakegawa86: Kakegawa T, Sato E, Hirose S, Igarashi K (1986). "Polyamine binding sites on Escherichia coli ribosomes." Arch Biochem Biophys 251(2);413-20. PMID: 3541786

Kamp82: Kamp R.M., Wittmann-Liebold B. (1982). "The primary structure of protein L9 from the Escherichia coli ribosome." FEBS Lett., Volume 149, page(s) 313-319.

Kamp83: Kamp RM, Yao ZJ, Wittmann-Liebold B (1983). "Direct micro-sequence analysis of peptides from Escherichia coli ribosomal proteins S11, L9 and L29 after separation by reversed phase chromatography." Hoppe Seylers Z Physiol Chem 364(2);141-55. PMID: 6341200

Kitakawa80: Kitakawa M, Blumenthal L, Isono K (1980). "Isolation and characterization of specialized transducing lambda phages carrying ribosomal protein genes of Escherichia coli." Mol Gen Genet 180(2);343-9. PMID: 6450872

Kuroda01: Kuroda A, Nomura K, Ohtomo R, Kato J, Ikeda T, Takiguchi N, Ohtake H, Kornberg A (2001). "Role of inorganic polyphosphate in promoting ribosomal protein degradation by the Lon protease in E. coli." Science 293(5530);705-8. PMID: 11474114

Lieberman00: Lieberman KR, Firpo MA, Herr AJ, Nguyenle T, Atkins JF, Gesteland RF, Noller HF (2000). "The 23 S rRNA environment of ribosomal protein L9 in the 50 S ribosomal subunit." J Mol Biol 297(5);1129-43. PMID: 10764578

LopezCampistrou05: Lopez-Campistrous A, Semchuk P, Burke L, Palmer-Stone T, Brokx SJ, Broderick G, Bottorff D, Bolch S, Weiner JH, Ellison MJ (2005). "Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth." Mol Cell Proteomics 4(8);1205-9. PMID: 15911532

Marquardt79: Marquardt O, Roth HE, Wystup G, Nierhaus KH (1979). "Binding of Escherichia coli ribosomal proteins to 23S RNA under reconstitution conditions for the 50S subunit." Nucleic Acids Res 6(11);3641-50. PMID: 386275

Matadeen99: Matadeen R, Patwardhan A, Gowen B, Orlova EV, Pape T, Cuff M, Mueller F, Brimacombe R, van Heel M (1999). "The Escherichia coli large ribosomal subunit at 7.5 A resolution." Structure 7(12);1575-83. PMID: 10647188

Morrison77: Morrison CA, Tischendorf G, Stoffler G, Garrett RA (1977). "Accessibility of proteins in 50S ribosomal subunits of Escherichia coli to antibodies: an ultracentrifugation study." Mol Gen Genet 151(3);245-52. PMID: 68433

Moureau83: Moureau P, Di Giambattista M, Cocito C (1983). "The lasting ribosome alteration produced by virginiamycin M disappears upon removal of certain ribosomal proteins." Biochim Biophys Acta 739(2);164-72. PMID: 6402016

Nag91: Nag B, Akella SS, Cann PA, Tewari DS, Glitz DG, Traut RR (1991). "Monoclonal antibodies to Escherichia coli ribosomal proteins L9 and L10. Effects on ribosome function and localization of L9 on the surface of the 50 S ribosomal subunit." J Biol Chem 266(33);22129-35. PMID: 1939233

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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