This view shows enzymes only for those organisms listed below, in the list of taxa known to possess the pathway. If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.
|Superclasses:||Biosynthesis → Secondary Metabolites Biosynthesis → Terpenoids Biosynthesis → Sesquiterpenoids Biosynthesis|
Expected Taxonomic Range: Viridiplantae
The sesqueterpenoids α-curcumene, (-)-β-curcumene and γ-curcumene are produced by plants as insect repellents and insect feeding deterrents [Antonious03a]. α-curcumene is a chief constituent of the essential oils of Curcuma longa and is synthesized as a racemic mixture of (+)-α-curcumene and (-)-α-curcumene.
Deguerry06: Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M (2006). "The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases." Arch Biochem Biophys 454(2);123-36. PMID: 16970904
Faraldos10: Faraldos JA, O'Maille PE, Dellas N, Noel JP, Coates RM (2010). "Bisabolyl-derived sesquiterpenes from tobacco 5-epi-aristolochene synthase-catalyzed cyclization of (2Z,6E)-farnesyl diphosphate." J Am Chem Soc 132(12);4281-9. PMID: 20201526
Martin10: Martin DM, Aubourg S, Schouwey MB, Daviet L, Schalk M, Toub O, Lund ST, Bohlmann J (2010). "Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays." BMC Plant Biol 10;226. PMID: 20964856
Noel10: Noel JP, Dellas N, Faraldos JA, Zhao M, Hess BA, Smentek L, Coates RM, O'Maille PE (2010). "Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates." ACS Chem Biol 5(4);377-92. PMID: 20175559
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