MetaCyc Transporter: Enzyme IIscr

Gene: scrA Accession Number: G-9676 (MetaCyc)

Species: Staphylococcus xylosus

The molecular weight of the recombinant enzyme overexpressed in Escherichia coli was determined by SDS-PAGE [Wagner93].

Locations: plasma membrane

Molecular Weight of Polypeptide: 51.326 kD (from nucleotide sequence), 50 kD (experimental) [Wagner93 ]

Unification Links: Protein Model Portal:P51184 , UniProt:P51184

Relationship Links: Entrez-Nucleotide:PART-OF:X69800 , InterPro:IN-FAMILY:IPR001996 , InterPro:IN-FAMILY:IPR003352 , InterPro:IN-FAMILY:IPR010973 , InterPro:IN-FAMILY:IPR013013 , InterPro:IN-FAMILY:IPR018113 , Pfam:IN-FAMILY:PF00367 , Pfam:IN-FAMILY:PF02378 , Prosite:IN-FAMILY:PS01035 , Prosite:IN-FAMILY:PS51098 , Prosite:IN-FAMILY:PS51103

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

GO Terms:

Cellular Component: GO:0016020 - membrane [Wagner93]

Enzymatic reaction of: Enzyme IIscr

Synonyms: EIIscr, EIIBCscr

Transport reaction diagram for Enzyme IIscr

The sucrose-specific Enzyme II component of the phosphoenolpyruvate-phosphotransferase system functions as a permease, mediating transport and phosphorylation of sucrose to sucrose-6-phosphate. In Staphylococcus xylosus the EIIscr polypeptide contains the B and C domains, but it is not clear which component of the PTS interacts with it to provide A domain function. Sucrose uptake by cultured cells was measured using [14C]sucrose [Wagner93].


Wagner93: Wagner E, Gotz F, Bruckner R (1993). "Cloning and characterization of the scrA gene encoding the sucrose-specific Enzyme II of the phosphotransferase system from Staphylococcus xylosus." Mol Gen Genet 241(1-2);33-41. PMID: 8232209

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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