|Gene:||apgM1||Accession Number: G-3787 (MetaCyc)|
Synonyms: pgm, MJ1612, iPGM
Species: Methanocaldococcus jannaschii
The interconversion of 3-phosphoglycerate and 2-phosphoglycerate during glycolysis and gluconeogenesis is catalyzed by phosphoglycerate mutase (PGM). In bacteria and eukaryotes two structurally distinct enzymes have been found, a cofactor-dependent (dPGM) and a cofactor-independent (iPGM) type.
Archaebacteria possess a new family of PGM proteins, distantly related to iPGMs.
Molecular Weight of Polypeptide: 45.226 kD (from nucleotide sequence), 45.2 kD (experimental) [vanderOost02 ]
Molecular Weight of Multimer: 190.6 kD (experimental) [vanderOost02]
Relationship Links: Entrez-Nucleotide:PART-OF:AAB99632 , InterPro:IN-FAMILY:IPR004456 , InterPro:IN-FAMILY:IPR006124 , InterPro:IN-FAMILY:IPR017849 , InterPro:IN-FAMILY:IPR017850 , InterPro:IN-FAMILY:IPR023665 , Pfam:IN-FAMILY:PF01676 , Pfam:IN-FAMILY:PF10143
|MultiFun Terms:||metabolism → carbon utilization → carbon compounds|
Enzymatic reaction of: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
EC Number: 126.96.36.199
The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.
This reaction is reversible.
Primary Physiological Regulators of Enzyme Activity: Mg2+
T(opt): 90 °C [vanderOost02]
pH(opt): 8 [vanderOost02]
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