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Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
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MetaCyc Enzyme: jasmonoyl-amino acid synthetase

Gene: JAR4 Accession Number: G-11278 (MetaCyc)

Synonyms: JA-amino synthetase, JA-amido conjugate synthetase, jasmonic acid:amino acid synthetase, jasmonate:amino acid synthetase, jasmonate:amino acid ligase (AMP-forming), jasmonyl-amino acid synthetase

Species: Nicotiana attenuata

Summary:
JAR4 is a jasmonyl-amino acid synthetase that is up-regulated, at the transcriptional level, in response to wounding, or wounding and treatment with the oral secretions of the herbivorous tobacco hornworm (Manduca sexta) [Wang07b]. Plants with reduced levels of JAR4 transcripts produce lower amounts of JA-isoleucine [Wang07b, Kang06], JA-leucine, and JA-valine [Wang07b], suggesting that this enzyme is involved in the production of those compounds in vivo.

Unification Links: NCBI Entrez Protein (GI):86212374

Relationship Links: Entrez-Nucleotide:PART-OF:DQ359729

Gene-Reaction Schematic: ?

Credits:
Created 23-Apr-2009 by Dreher KA , TAIR


Enzymatic reaction of: jasmonoyl-leucine synthetase (jasmonoyl-amino acid synthetase)

Synonyms: JA-Leu synthetase, jasmonate-leucine synthetase, jasmonic acid-leucine synthetase, jasmonate:leucine ligase (AMP-forming), jasmonyl-leucine synthetase

EC Number: 6.3.-.-

a jasmonic acid + L-leucine + ATP <=> a jasmonoyl-leucine + AMP + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: superpathway of jasmonoyl-amino acid conjugates biosynthesis , jasmonoyl-amino acid conjugates biosynthesis II


Enzymatic reaction of: jasmonoyl-valine synthetase (jasmonoyl-amino acid synthetase)

Synonyms: JA-Val synthetase, jasmonate-valine synthetase, jasmonic acid-valine synthetase, jasmonate:valine ligase (AMP-forming), jasmonyl-valine synthetase

EC Number: 6.3.-.-

a jasmonic acid + L-valine + ATP <=> a jasmonoyl-valine + AMP + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: superpathway of jasmonoyl-amino acid conjugates biosynthesis , jasmonoyl-amino acid conjugates biosynthesis II


Enzymatic reaction of: jasmonoyl-isoleucine synthetase (jasmonoyl-amino acid synthetase)

Synonyms: JA-Ile synthetase, jasmonate-isoleucine synthetase, jasmonic acid-isoleucine synthetase, jasmonate:isoleucine ligase (AMP-forming), jasmonyl-isoleucine synthetase

EC Number: 6.3.-.-

a jasmonic acid + L-isoleucine + ATP <=> a jasmonoyl-isoleucine + AMP + diphosphate

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

The reaction is physiologically favored in the direction shown.

In Pathways: superpathway of jasmonoyl-amino acid conjugates biosynthesis , jasmonoyl-amino acid conjugates biosynthesis II


References

Kang06: Kang JH, Wang L, Giri A, Baldwin IT (2006). "Silencing threonine deaminase and JAR4 in Nicotiana attenuata impairs jasmonic acid-isoleucine-mediated defenses against Manduca sexta." Plant Cell 18(11);3303-20. PMID: 17085687

Wang07b: Wang L, Halitschke R, Kang JH, Berg A, Harnisch F, Baldwin IT (2007). "Independently silencing two JAR family members impairs levels of trypsin proteinase inhibitors but not nicotine." Planta 226(1);159-67. PMID: 17273867


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Sun Nov 23, 2014, biocyc14.