MetaCyc Enzyme: glycine decarboxylase

Gene: AT2G35120

Species: Arabidopsis thaliana col

Subunit composition of glycine decarboxylase = [glycine decarboxylase T protein][glycine decarboxylase P protein][glycine decarboxylase L protein][AT2G35120]
         glycine decarboxylase H protein = AT2G35120

Glycine decarboxylase in plants is a multi enzyme complex. It is generally composed of 4 proteins, a 100 KD P-protein, a 14 KD H-protein, a 45 KD T-protein, and a 59 KD L-protein [Walker86].
glycine decarboxylase complex H-protein

Locations: mitochondrion

Unification Links: String:3702.AT2G35120.1, TAIR:AT2G35120

Gene-Reaction Schematic

Gene-Reaction Schematic

GO Terms:
Cellular Component:
GO:0005739 - mitochondrion []

Enzymatic reaction of: glycine decarboxylase

Inferred from experimentInferred by computational analysis

Synonyms: GDC

glycine + a tetrahydrofolate + NAD+ → a 5,10-methylene-tetrahydrofolate + ammonium + CO2 + NADH

The direction shown, i.e. which substrates are on the left and right sides, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: folate transformations II, photorespiration

Subunit of glycine decarboxylase: glycine decarboxylase T protein

Subunit of glycine decarboxylase: glycine decarboxylase P protein

Subunit of glycine decarboxylase: glycine decarboxylase L protein

Subunit of glycine decarboxylase: glycine decarboxylase H protein

Synonyms: AT2G35120

Gene: AT2G35120

Unification Links: PhylomeDB:O82179, Pride:O82179, Protein Model Portal:O82179, SMR:O82179, UniProt:O82179

Relationship Links: InterPro:IN-FAMILY:IPR000089, InterPro:IN-FAMILY:IPR002930, InterPro:IN-FAMILY:IPR003016, InterPro:IN-FAMILY:IPR011053, InterPro:IN-FAMILY:IPR017453, Panther:IN-FAMILY:PTHR11715, Pfam:IN-FAMILY:PF01597, Prosite:IN-FAMILY:PS00189, Prosite:IN-FAMILY:PS50968


Walker86: Walker JL, Oliver DJ (1986). "Glycine decarboxylase multienzyme complex. Purification and partial characterization from pea leaf mitochondria." J Biol Chem 1986;261(5);2214-21. PMID: 3080433

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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