MetaCyc Enzyme: glycine decarboxylase

Gene: AT2G35120

Species: Arabidopsis thaliana col

Subunit composition of glycine decarboxylase = [glycine decarboxylase T protein][glycine decarboxylase P protein][glycine decarboxylase L protein][AT2G35120]
         glycine decarboxylase H protein = AT2G35120

Glycine decarboxylase in plants is a multi enzyme complex. It is generally composed of 4 proteins, a 100 KD P-protein, a 14 KD H-protein, a 45 KD T-protein, and a 59 KD L-protein [Walker86].
glycine decarboxylase complex H-protein

Locations: mitochondrion

Unification Links: TAIR:AT2G35120

Gene-Reaction Schematic: ?

Gene-Reaction Schematic

GO Terms:

Cellular Component: GO:0005739 - mitochondrion

Enzymatic reaction of: glycine decarboxylase

Synonyms: GDC

glycine + a tetrahydrofolate + NAD+ <=> a 5,10-methylene-tetrahydrofolate + ammonium + CO2 + NADH

The reaction direction shown, that is, A + B ↔ C + D versus C + D ↔ A + B, is in accordance with the direction in which it was curated.

This reaction is reversible.

In Pathways: folate transformations II , photorespiration

Subunit of glycine decarboxylase: glycine decarboxylase T protein

Subunit of glycine decarboxylase: glycine decarboxylase P protein

Subunit of glycine decarboxylase: glycine decarboxylase L protein

Subunit of glycine decarboxylase: glycine decarboxylase H protein

Synonyms: AT2G35120

Gene: AT2G35120

Unification Links: PhylomeDB:O82179 , Pride:O82179 , Protein Model Portal:O82179 , SMR:O82179 , String:3702.AT2G35120.1-P , UniProt:O82179

Relationship Links: InterPro:IN-FAMILY:IPR002930 , InterPro:IN-FAMILY:IPR003016 , InterPro:IN-FAMILY:IPR011053 , InterPro:IN-FAMILY:IPR017453 , Panther:IN-FAMILY:PTHR11715 , Pfam:IN-FAMILY:PF01597 , Prosite:IN-FAMILY:PS00189


Walker86: Walker JL, Oliver DJ (1986). "Glycine decarboxylase multienzyme complex. Purification and partial characterization from pea leaf mitochondria." J Biol Chem 1986;261(5);2214-21. PMID: 3080433

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Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
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