Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
Metabolic Modeling Tutorial
discounted EARLY registration ends Dec 31, 2014
twitter

MetaCyc Polypeptide: phthiocerol/phenolphthiocerol synthesis polyketide synthase type I

Gene: ppsA Accession Number: G-15029 (MetaCyc)

Synonyms: β-ketoacyl-acyl-carrier-protein synthase I

Species: Mycobacterium bovis

Summary:
Catalyzes the condensation of C22-24 fatty acids or p-hydroxyphenylalkanoic acids with malonyl-CoA and methylmalonyl-CoA to yield either phthiocerol and phenolphthiocerol derivatives respectively [Azad97].

Molecular Weight of Polypeptide: 198.84 kD (from nucleotide sequence)

Unification Links: Protein Model Portal:Q7TXM0 , String:233413.Mb2956 , UniProt:Q7TXM0

Relationship Links: InterPro:IN-FAMILY:IPR001227 , InterPro:IN-FAMILY:IPR006162 , InterPro:IN-FAMILY:IPR009081 , InterPro:IN-FAMILY:IPR013968 , InterPro:IN-FAMILY:IPR014030 , InterPro:IN-FAMILY:IPR014031 , InterPro:IN-FAMILY:IPR014043 , InterPro:IN-FAMILY:IPR016035 , InterPro:IN-FAMILY:IPR016036 , InterPro:IN-FAMILY:IPR016038 , InterPro:IN-FAMILY:IPR016039 , InterPro:IN-FAMILY:IPR016040 , InterPro:IN-FAMILY:IPR018201 , InterPro:IN-FAMILY:IPR020801 , InterPro:IN-FAMILY:IPR020806 , InterPro:IN-FAMILY:IPR020841 , InterPro:IN-FAMILY:IPR020842 , Panther:IN-FAMILY:PTHR11712 , Pfam:IN-FAMILY:PF00109 , Pfam:IN-FAMILY:PF00550 , Pfam:IN-FAMILY:PF00698 , Pfam:IN-FAMILY:PF02801 , Pfam:IN-FAMILY:PF08659 , Prosite:IN-FAMILY:PS00012 , Prosite:IN-FAMILY:PS00606 , Prosite:IN-FAMILY:PS50075 , Smart:IN-FAMILY:SM00822 , Smart:IN-FAMILY:SM00823 , Smart:IN-FAMILY:SM00825 , Smart:IN-FAMILY:SM00827

Credits:
Created 09-Mar-2012 by Weerasinghe D , SRI International


References

Azad97: Azad AK, Sirakova TD, Fernandes ND, Kolattukudy PE (1997). "Gene knockout reveals a novel gene cluster for the synthesis of a class of cell wall lipids unique to pathogenic mycobacteria." J Biol Chem 272(27);16741-5. PMID: 9201977


Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 42:D459-D471 2014
Page generated by SRI International Pathway Tools version 18.5 on Wed Nov 26, 2014, BIOCYC14B.